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Special Issue "Nanoparticles for Drug Delivery and Biosensing Applications"

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: closed (30 December 2019).

Special Issue Editor

Prof. Suresh Gadde
E-Mail Website
Guest Editor
Department of Biochemistry, Microbiology and Immunology Faculty of Medicine, University of Ottawa, Canada
Interests: Nanomedicine; Nano-Biomaterials; Targeted nanotherapeutics; Nanoparticles; Cancer nanomedicine

Special Issue Information

Dear Colleagues,

The growing interest in nanotechnology-based applications in medicine is attributed to their uniquely appealing features for drug delivery, imaging, tissue engineering, and medical device development. Several nanotechnology-based therapeutic platforms are either in clinic or under clinical investigation. These platforms have several benefits such as targeted delivery, controlled drug release, ability to encapsulate a wide variety of therapeutic agents, and multi-drug delivery. Recent advances in biomaterials design and synthesis, coupled with a better understanding of nano-bio interactions, enabled the development of more sophisticated platforms. They include, but are not limited to, stimuli response, supramolecular host-guest, redox sensitive, drug delivery sensors, on-demand drug delivery, and guided drug delivery; and their applications range from cancer, cardiovascular diseases, and inflammation, to neurodegenerative diseases.  

The main goal of this Special Issue is to capture the current state-of-the-art and contemporary progress in a variety of nano-biomaterials and nanomedicines development and their different disease applications. Suggested drug-delivery topics are smart platforms, redox active, stimuli-responsive, supramolecular, targeted drug delivery, drug-delivery sensors, and imaging-guided therapeutic platforms. Both research papers and review articles will be considered. If you are interested in contributing to this Special Issue, I would very much appreciate receiving the tentative title of your contribution.

Prof. Suresh Gadde
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • drug delivery
  • smart materials 
  • stimuli responsive drug delivery 
  • supramolecular biomaterials
  • nanomedicine 
  • multi-functional materials 
  • controlled release 
  • sensors-based drug-delivery 
  • on-demand drug-delivery 
  • biosensors drug delivery

Published Papers (1 paper)

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Research

Open AccessArticle
Colorimetric Analysis of Glucose Oxidase-Magnetic Cellulose Nanocrystals (CNCs) for Glucose Detection
Sensors 2019, 19(11), 2511; https://doi.org/10.3390/s19112511 - 31 May 2019
Cited by 1
Abstract
Glucose oxidase (EC 1.1.3.4) sensors that have been developed and widely used for glucose monitoring have generally relied on electrochemical principle. In this study, the potential use of colorimetric method for glucose detection utilizing glucose oxidase-magnetic cellulose nanocrystals (CNCs) is explored. Magnetic cellulose [...] Read more.
Glucose oxidase (EC 1.1.3.4) sensors that have been developed and widely used for glucose monitoring have generally relied on electrochemical principle. In this study, the potential use of colorimetric method for glucose detection utilizing glucose oxidase-magnetic cellulose nanocrystals (CNCs) is explored. Magnetic cellulose nanocrystals (magnetic CNCs) were fabricated using iron oxide nanoparticles (IONPs) and cellulose nanocrystals (CNCs) via electrostatic self-assembly technique. Glucose oxidase was successfully immobilized on magnetic CNCs using carbodiimide-coupling reaction. About 33% of GOx was successfully attached on magnetic CNCs, and the affinity of GOx-magnetic CNCs to glucose molecules was slightly higher than free enzymes. Furthermore, immobilization does not affect the specificity of GOx-magnetic CNCs towards glucose and can detect glucose from 0.25 mM to 2.5 mM. Apart from that, GOx-magnetic CNCs stored at 4 °C for 4 weeks retained 70% of its initial activity and can be recycled for at least ten consecutive cycles. Full article
(This article belongs to the Special Issue Nanoparticles for Drug Delivery and Biosensing Applications)
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