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Nanomaterial-Driven Innovations in Biosensing and Healthcare

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biomedical Sensors".

Deadline for manuscript submissions: 25 November 2025 | Viewed by 1285

Special Issue Editor


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Guest Editor
MEMS and Nanotechnology Laboratory, Advanced Medical Device Research Center for Cardiovascular Disease, School of Mechanical Engineering, Chonnam National University, Gwangju 61186, Republic of Korea
Interests: nanomaterial-based sensors for biomedical applications; gas sensors for biomedical applications; microfabrication and functional materials for sensing applications

Special Issue Information

Dear Colleagues,

The integration of smart nanomaterials in biomedical sensing has revolutionized healthcare diagnostics, enabling the highly sensitive, selective, and real-time monitoring of various biomarkers and physiological parameters. These nanomaterials, including metal and metal oxide nanoparticles, carbon-based nanostructures, 2D materials, and functionalized polymers, exhibit unique physicochemical properties such as high surface area-to-volume ratio, quantum confinement effects, and excellent charge transport capabilities, which significantly enhance sensor performance. Their tunable surface chemistry, biocompatibility, and ability to interact with biomolecules at the nanoscale have led to significant advancements in point-of-care diagnostics, wearable biosensors, and implantable devices for continuous health monitoring. Furthermore, the integration of nanomaterials with microfluidic platforms and artificial intelligence-based data analysis has enabled multiplexed detection and improved sensitivity in biomedical applications. This Special Issue aims at exploring recent developments in nanomaterial-based biosensors for detecting diseases, monitoring metabolic parameters, and facilitating early-stage diagnostics. We welcome contributions covering novel sensor architectures, functionalization strategies, signal transduction mechanisms, and real-world applications of nanomaterials in biosensing. Topics of interest include electrochemical, optical, and flexible biosensors, as well as advancements in miniaturized and wireless sensing platforms.

This Special Issue aligns with the scope of Sensors by addressing innovative sensing technologies that enhance healthcare, disease management, and personalized medicine.

Dr. Arunkumar Shanmugasundaram
Guest Editor

Manuscript Submission Information

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Keywords

  • smart nanomaterials
  • biosensors
  • biomedical sensing
  • point-of-care diagnostics
  • wearable sensors
  • electrochemical sensors

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Published Papers (1 paper)

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Review

62 pages, 4690 KiB  
Review
Functional Nanomaterials for Advanced Bioelectrode Interfaces: Recent Advances in Disease Detection and Metabolic Monitoring
by Junlong Ma, Siyi Yang, Zhihao Yang, Ziliang He and Zhanhong Du
Sensors 2025, 25(14), 4412; https://doi.org/10.3390/s25144412 - 15 Jul 2025
Viewed by 1133
Abstract
As critical interfaces bridging biological systems and electronic devices, the performance of bioelectrodes directly determines the sensitivity, selectivity, and reliability of biosensors. Recent advancements in functional nanomaterials (e.g., carbon nanomaterials, metallic nanoparticles, 2D materials) have substantially enhanced the application potential of bioelectrodes in [...] Read more.
As critical interfaces bridging biological systems and electronic devices, the performance of bioelectrodes directly determines the sensitivity, selectivity, and reliability of biosensors. Recent advancements in functional nanomaterials (e.g., carbon nanomaterials, metallic nanoparticles, 2D materials) have substantially enhanced the application potential of bioelectrodes in disease detection, metabolic monitoring, and early diagnosis through strategic material selection, structural engineering, interface modification, and antifouling treatment. This review systematically examines the latest progress in nanomaterial-enabled interface design of bioelectrodes, with particular emphasis on performance enhancements in electrophysiological/electrochemical signal acquisition and multimodal sensing technologies. We comprehensively analyze cutting-edge developments in dynamic metabolic parameter monitoring for chronic disease management, as well as emerging research on flexible, high-sensitivity electrode interfaces for early disease diagnosis. Furthermore, this work focused on persistent technical challenges regarding nanomaterial biocompatibility and long-term operational stability while providing forward-looking perspectives on their translational applications in wearable medical devices and personalized health management systems. The proposed framework offers actionable guidance for researchers in this interdisciplinary field. Full article
(This article belongs to the Special Issue Nanomaterial-Driven Innovations in Biosensing and Healthcare)
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