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Multifunctional Materials Sensors for Theranostic Nanomedicine

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Sensor Materials".

Deadline for manuscript submissions: closed (31 May 2021) | Viewed by 6940

Special Issue Editor


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Guest Editor
Department of Chemical Sciences, University of Catania, 95125 Catania, Italy
Interests: smart materials; nanomaterials; hybrid biointerfaces; theranostics; nanomedicine
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Sensors welcomes submissions to this Special Issue entitled “Multifunctional Materials Sensors for Theranostic Nanomedicine”.

Nanomaterials exhibit unique properties that are not found in bulk materials; today, thanks to the tremendous advances in the fabrication and in the monitoring approaches of nanotechnology devices, multifunctionality can be easily achieved either on a single (nano)material or by integrating several types of materials in composite nanostructures.

The high surface-to-volume ratio of the matter structured at the nanoscale allows for a tunable morphology and ease of modification through surface tailoring. These features, coupled with other characteristics, such as optoelectronic and magnetic properties as well as biocompatibility, can exploited to achieve theranostic capabilities (i.e., merging diagnostic and therapeutic functionalities) and multimodality for sensing/imaging applications. Therefore, combined with imaging techniques, multifunctional nanomedicines with theranostic properties can simultaneously provide imaging, diagnosis, and treatment in the same administration to overcome current limits of conventional therapy.

The main themes and keywords to guide potential authors are as follows:

  1. Multimodal imaging applications that use nanoparticles, with a particular interest in real-time monitoring of therapeutic molecules as well as imaging and diagnosis tools.
  2. Challenges and perspectives with nanoparticles with sensing capabilities in medicine.
  3. Nanotechnology-based approaches for developing multifunctional and targeting strategies, leading simultaneously toward the detection, diagnosis, and treatment of cancer and other diseases.

Dr. Cristina Satriano
Guest Editor

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Published Papers (1 paper)

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Review

22 pages, 2261 KiB  
Review
The Application of Prussian Blue Nanoparticles in Tumor Diagnosis and Treatment
by Xiaoran Gao, Qiaowen Wang, Cui Cheng, Shujin Lin, Ting Lin, Chun Liu and Xiao Han
Sensors 2020, 20(23), 6905; https://doi.org/10.3390/s20236905 - 3 Dec 2020
Cited by 35 | Viewed by 6257
Abstract
Prussian blue nanoparticles (PBNPs) have attracted increasing research interest in immunosensors, bioimaging, drug delivery, and application as therapeutic agents due to their large internal pore volume, tunable size, easy synthesis and surface modification, good thermal stability, and favorable biocompatibility. This review first outlines [...] Read more.
Prussian blue nanoparticles (PBNPs) have attracted increasing research interest in immunosensors, bioimaging, drug delivery, and application as therapeutic agents due to their large internal pore volume, tunable size, easy synthesis and surface modification, good thermal stability, and favorable biocompatibility. This review first outlines the effect of tumor markers using PBNPs-based immunosensors which have a sandwich-type architecture and competitive-type structure. Metal ion doped PBNPs which were used as T1-weight magnetic resonance and photoacoustic imaging agents to improve image quality and surface modified PBNPs which were used as drug carriers to decrease side effects via passive or active targeting to tumor sites are also summarized. Moreover, the PBNPs with high photothermal efficiency and excellent catalase-like activity were promising for photothermal therapy and O2 self-supplied photodynamic therapy of tumors. Hence, PBNPs-based multimodal imaging-guided combinational tumor therapies (such as chemo, photothermal, and photodynamic therapies) were finally reviewed. This review aims to inspire broad interest in the rational design and application of PBNPs for detecting and treating tumors in clinical research. Full article
(This article belongs to the Special Issue Multifunctional Materials Sensors for Theranostic Nanomedicine)
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