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Biosensors and Integrated Therapeutics for Precision Health

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Wearables".

Deadline for manuscript submissions: 20 July 2026 | Viewed by 613

Special Issue Editors


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Guest Editor
Department of Chemical and Nano Engineering, University of California San Diego, 9500 Gilman Dr, La Jolla, San Diego, CA 92093, USA
Interests: biosensors; electrochemical sensors; wearable sensors; aptamer-based sensors

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Guest Editor Assistant
1 Department of Chemical and Nano Engineering, University of California San Diego, 9500 Gilman Dr, La Jolla, San Diego, CA 92093, USA
2 King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia
Interests: biosensors; nanomotors; wearable sensors; diagnostic devices; touch-based sensors, drug delivery

Special Issue Information

Dear Colleagues,

Advances in biosensor/sensor technology are transforming healthcare by enabling continuous, real-time, and non-invasive or minimally invasive monitoring of physiological and biochemical signals. From point of care devices, wearable patches, and implantable micro-devices to touch-based interfaces for health monitoring, these systems are driving the next generation of precision health. Furthermore, emerging platforms integrate therapeutic actuation capabilities, such as drug delivery, electrical stimulation, or mechanical response, creating closed-loop systems that can sense, analyze, and respond to individual needs.

This Special Issue will focus on developments in the emerging space of precision health, highlighting various recent developments in device design, sensing modalities, data analytics, and clinical applications, aiming to bridge the gap between engineering advances and real-world healthcare impacts.

We welcome original research articles, reviews, short communications, and clinical or translational studies that advance the field of health-focused sensing technologies. Submissions may address novel materials, device architectures, sensing mechanisms, analytical algorithms, integration with telemedicine and IoMT platforms, or validation in laboratory, preclinical, or clinical settings. Studies should emphasize innovation, scalability, and the potential to improve patient outcomes in personalized, preventive, and precision medicine.

Dr. Kuldeep Mahato
Guest Editor

Dr. Amal Abbas
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biosensors
  • chemical sensors
  • precision health
  • therapeutic drug monitoring
  • wearable sensors
  • implantable sensors
  • disposable sensors
  • point of care sensors
  • closed-loop devices

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Published Papers (1 paper)

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Review

21 pages, 2539 KB  
Review
Recent Advances in Bacterial Separation and Enrichment from Blood for the Diagnosis of Bloodstream Infections
by Hai-Bo Wang, Zhen-Zheng Zhang, Qing Liu, Hang-Bo Lu, Jian-Hui Jiang, Ru-Qin Yu and Hao Tang
Sensors 2026, 26(11), 3371; https://doi.org/10.3390/s26113371 - 26 May 2026
Viewed by 213
Abstract
In this paper, recent advances (2016–2026) in bacterial separation and enrichment from blood for diagnosis of bloodstream infection (BSIs) through pathogen identification and antimicrobial susceptibility testing (AST) are reviewed. The review centers on sample processing as an indispensable front-end of biosensor and lab-on-chip [...] Read more.
In this paper, recent advances (2016–2026) in bacterial separation and enrichment from blood for diagnosis of bloodstream infection (BSIs) through pathogen identification and antimicrobial susceptibility testing (AST) are reviewed. The review centers on sample processing as an indispensable front-end of biosensor and lab-on-chip platforms, since most sensors cannot operate directly in whole blood. Efficient separation and enrichment concentrate extremely low bacterial burdens, remove blood components that interfere with detection, and deliver bacteria in a sensor-compatible format; consequently, diagnostic sensitivity, specificity, turnaround time, and robustness are strongly determined by this step. We first summarize the clinical impact of BSIs and the value of rapid AST for guiding timely, targeted therapy, emphasizing that efficient bacterial isolation from blood is a prerequisite for accurate testing. We then discuss key challenges and recent progress in bacterial separation and enrichment from blood with major approaches, including filtration, centrifugation, functionalized magnetic beads, and microfluidic technologies. These strategies serve as core building blocks that interface with downstream identification and AST methods, supporting integrated biosensors and point-of-care devices. Finally, we outline future directions of bacterial separation and enrichment approaches to improve recovery, purity, integration, standardization, and overall diagnostic performance for BSI workflows. Full article
(This article belongs to the Special Issue Biosensors and Integrated Therapeutics for Precision Health)
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