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EEG Signal Processing in Healthcare, Cognitive Neuroscience, and Medical Diagnosis

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Intelligent Sensors".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 622

Special Issue Editors


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Guest Editor
Department of Electrical and Computer Engineering, Faculty of Engineering, University of Western Macedonia, 50100 Kozani, Greece
Interests: biosignal processing; brain–computer interfaces and wearable devices for movement and brain disorder analysis

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Guest Editor Assistant
Department of Informatics and Telecommunications, University of Ioannina, 47100 Arta, Greece
Interests: EEG signal processing and machine learning; particularly in dementia diagnosis; BCI applications; medical image analysis and classification

Special Issue Information

Dear Colleagues,

In recent years, electroencephalography (EEG) has resurfaced as a promising tool for enhancing our understanding of brain function and supporting clinical practice, including the diagnosis of various conditions such as epilepsy and encephalopathy, while being researched for conditions like Alzheimer’s disease. It is also employed in cognitive neuroscience research and healthcare monitoring. With the integration of advanced signal processing techniques and machine learning, it is now widely studied in detecting neurological disorders, monitoring brain health, and understanding cognitive states and behavioural processes.

This Special Issue focuses on the role of EEG signal processing in addressing challenges in medical diagnosis, clinical applications, and cognitive or applied contexts. Beyond traditional medical diagnosis, the scope of this Special Issue also includes cognitive neuroscience applications such as neuroergonomics, affective neuroscience, cognitive workload assessment, decision-making analysis and brain–computer interfaces (BCIs), among other topics. Additionally, automated machine learning and deep learning methodologies for medical diagnosis or evaluation using EEG signals are also integral to the scope.

Papers submitted to this Special Issue should demonstrate novel and innovative applications, covering topics such as the following:

  • Machine learning for EEG analysis and artifact removal.
  • EEG in clinical diagnosis and healthcare.
  • Cognitive neuroscience applications of EEG.
  • Brain modeling and network analysis with EEG.
  • Advanced signal processing for EEG research.

Dr. Katerina D. Tzimourta
Dr. Alexandros Tzallas
Guest Editors

Dr. Andreas Miltiadous
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • EEG signal processing
  • cognitive neuroscience
  • medical diagnosis
  • brain health monitoring
  • brain–computer interfaces
  • brain network analysis
  • machine learning

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Published Papers (1 paper)

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Research

25 pages, 2026 KiB  
Article
EEG Signal Prediction for Motor Imagery Classification in Brain–Computer Interfaces
by Óscar Wladimir Gómez-Morales, Diego Fabian Collazos-Huertas, Andrés Marino Álvarez-Meza and Cesar German Castellanos-Dominguez
Sensors 2025, 25(7), 2259; https://doi.org/10.3390/s25072259 - 3 Apr 2025
Viewed by 536
Abstract
Brain–computer interfaces (BCIs) based on motor imagery (MI) generally require EEG signals recorded from a large number of electrodes distributed across the cranial surface to achieve accurate MI classification. Not only does this entail long preparation times and high costs, but it also [...] Read more.
Brain–computer interfaces (BCIs) based on motor imagery (MI) generally require EEG signals recorded from a large number of electrodes distributed across the cranial surface to achieve accurate MI classification. Not only does this entail long preparation times and high costs, but it also carries the risk of losing valuable information when an electrode is damaged, further limiting its practical applicability. In this study, a signal prediction-based method is proposed to achieve high accuracy in MI classification using EEG signals recorded from only a small number of electrodes. The signal prediction model was constructed using the elastic net regression technique, allowing for the estimation of EEG signals from 22 complete channels based on just 8 centrally located channels. The predicted EEG signals from the complete channels were used for feature extraction and MI classification. The results obtained indicate a notable efficacy of the proposed prediction method, showing an average performance of 78.16% in classification accuracy. The proposed method demonstrated superior performance compared to the traditional approach that used few-channel EEG and also achieved better results than the traditional method based on full-channel EEG. Although accuracy varies among subjects, from 62.30% to an impressive 95.24%, these data indicate the capability of the method to provide accurate estimates from a reduced set of electrodes. This performance highlights its potential to be implemented in practical MI-based BCI applications, thereby mitigating the time and cost constraints associated with systems that require a high density of electrodes. Full article
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