Nucleic Acid-Based Biosensors for Molecular Diagnostics
A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 20
Special Issue Editor
Special Issue Information
Dear Colleagues,
Nucleic acid (DNA or RNA)-based biosensors leverage the high specificity of DNA/RNA hybridization, catalytic activity of nucleic acid−based enzymes (ribozymes and deoxyribozymes), and molecular recognition properties of aptamers to detect biomarkers with exceptional sensitivity and selectivity.
This Special Issue focuses on the cutting-edge advancements and applications of nucleic acid-based biosensors in molecular diagnostics. We welcome original research and reviews covering fundamental studies on probe design, novel transduction mechanisms, and translational applications in detecting infectious diseases, genetic disorders, cancer biomarkers, antimicrobial resistance, and other diseases.
Contributions highlighting real-world clinical validation, multiplexed detection, and low-cost solutions for resource-limited settings are particularly encouraged, aiming to bridge technological innovation with diagnostic needs.
Prof. Dr. Fei Ma
Guest Editor
Manuscript Submission Information
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Keywords
- nucleic acid biosensors
- molecular diagnostics
- signal amplification
- aptamer
- DNAzyme
- RNAzyme
- DNA nanodevice
- DNA nanotechnology
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