Red Blood Cell Multi-Omics
A special issue of Proteomes (ISSN 2227-7382).
Deadline for manuscript submissions: closed (31 July 2020) | Viewed by 6950
Special Issue Editors
Interests: molecular and cellular aging; erythrocyte; autoimmunity; membrane; signaling
Interests: mass spectrometry-based proteomics; malaria; Plasmodium falciparum; red blood cells; cancer; phosphorylation; signalling pathways; clinical proteomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Proteomic analyses have provided new information on and a new impetus for the study of the structure/function relationship of red blood cells, and concomitantly of the role of red blood cells in the maintenance of organismal homeostasis. Recent years have seen the supplementation of information from proteomic inventories with detailed metabolomic and, recently, lipidomic data. These developments have emphasized the need for a multi-omics, integrative approach in order to understand the physiological as well as pathological implications of emerging pathways, especially those that are not in the red blood cell physiology textbooks. Algorithms for multi-omics and phenotypical metadata are being established, together with biomathematical models of biochemical regulation. Once again, the red blood cell may serve as a model, in this case to evaluate the integrative power of such algorithms in the interpretation of physiological phenomena. In addition, recent developments on erythropoiesis in vitro provide genomic and transcriptomic possibilities to interpret the effects of (manipulation of) processes in the bone marrow on long term function and survival of mature red blood cells in the circulation.
We invite you to contribute original research, technical notes, method papers, and reviews on ‘Red Blood Cell Multi-omics’ that are centered around multiple -omics analyses of red blood cells and may include the study and manipulation of erythropoiesis in vitro, as well as physiological and pathological studies on mature red blood cells in vitro and in vivo.
Dr. Giel Bosman
Assoc. Prof. Edwin Lasonder
Guest Editor
Manuscript Submission Information
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Keywords
- anemia
- erythrocyte
- genomics
- lipidomics
- metabolomics
- multi-omics
- proteomics
- red blood cell
- transcriptomics
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