Drug Design, Synthesis, and Activity Studies of Diseases
A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Pharmaceutical Processes".
Deadline for manuscript submissions: closed (10 November 2023) | Viewed by 242
Special Issue Editors
Interests: chemical biology; drug discovery; molecular biology; cell biology
Interests: drug design; molecular glue degrader; antibody-drug conjugate; glutamine metabolism; innovative drug development
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Numerous new design ideas and strategies for the development of small molecule drugs have emerged, including targeted protein degradation (TPD), ADC, AI-based drug design, and so on. Among them, TPD has become a promising frontier in the discovery and development of innovative therapeutics, especially for proteins without ligands or lacking enzymatic function. The rise of this novel technology has to some extent resolved the difficulties faced by small molecule inhibitors. As a pharmacological strategy, TPD might destabilize proteins by hijacking the intracellular proteolysis machinery. At present, many protein degraders, PROTAC, and molecular glue are in the clinical research stage. We believe that in the near future, PROTAC will soon be launched for the treatment of various diseases.
This Special Issue will focus on the latest processes and strategies in the field of drug design, synthesis and activity study for disease, especially for the study of TPD.
Dr. Wenchao Lu
Dr. Xi Xu
Prof. Dr. Baishan Jiang
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- target protein degradation
- E3 Ubiqutin Ligase
- ubiquitin proteasome system
- glue molecule
- bifunctional molecule
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
