Synthesis, Isolation and Application of Carbohydrates

A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Chemical Processes and Systems".

Deadline for manuscript submissions: 20 March 2026 | Viewed by 510

Special Issue Editors


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Guest Editor
Division of Natural Sciences, College of Natural & Applied Sciences, University of Guam, Mangilao, GU 96923, USA
Interests: carbohydrate chemistry; medicinal chemistry; natural product research

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Guest Editor
College of Chemistry, Beijing Normal University, Beijing 100875, China
Interests: glycosylation; glycoconjugate; glycobiology

Special Issue Information

Dear Colleagues,

Carbohydrates, the most abundant natural products, play important roles in their biological activities, such as solubility, target binding, tissue targeting, and membrane transportation. In the past two decades, carbohydrates research has attracted increasing attention due to their biological significance and potential therapeutic application. However, the synthesis and isolation of carbohydrates remain a challenge because of their structural complexity. Even though carbohydrates play important roles in many biological processes, carbohydrate-containing drugs take only a small portion among all approved drugs. The purpose of this Special Issue is to promote the study of carbohydrates in carbohydrate chemistry, biology, and application of carbohydrates in drug development.

This Special Issue on “Synthesis, Isolation and Application of Carbohydrates” seeks high-quality works focusing on new scientific achievements and new methodology developments in the synthesis, separation, characterization, glycosylation, and potential biological and therapeutic application of carbohydrates in various areas.

Topics include, but are not limited to, new method developments and/or applications in the following areas:

  • Chemical synthesis of carbohydrates;
  • Enzymatic or chemoenzymatic synthesis of carbohydrates;
  • Isolation of carbohydrates from natural sources;
  • Structural characterization of carbohydrates;
  • Glycosylation of carbohydrates;
  • Biological or therapeutic application of carbohydrates.

Original research and reviews are welcome.

Dr. Bulan Wu
Prof. Dr. Guowen Xing
Guest Editors

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Keywords

  • carbohydrates
  • monosaccharides
  • disaccharides
  • oligosaccharides
  • polysaccharides
  • glycans
  • glycoconjugates
  • glycopolymers
  • glycosylation
  • chemoenzymatic synthesis

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Published Papers (1 paper)

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Research

8 pages, 2146 KiB  
Communication
Simple Boronic Acid-Appended Sensor Array for Saccharides by Linear Discriminant Analysis
by Guangjian Liu, Zi Long and Guowen Xing
Processes 2025, 13(8), 2323; https://doi.org/10.3390/pr13082323 - 22 Jul 2025
Viewed by 119
Abstract
Saccharides play important roles in human health and life. However, detecting and differentiating the saccharide types using one probe is difficult even under optimized conditions due to the similar structures of different saccharides. In this study, only one sensor was used to construct [...] Read more.
Saccharides play important roles in human health and life. However, detecting and differentiating the saccharide types using one probe is difficult even under optimized conditions due to the similar structures of different saccharides. In this study, only one sensor was used to construct the array for the discrimination of different types of saccharides on the basis of a dialdehyde-diboronic acid-functionalized tetraphenylethene (TPE-DABA) under different pH conditions. By integrating the fluorescence responses of the probe with linear discriminant analysis (LDA), 12 kinds of saccharides and the polyhydroxy compound sorbitol could be distinguished and identified by as few as one sensor probe. This study provides a reference for developing more simple and effective sensor arrays for saccharides. Full article
(This article belongs to the Special Issue Synthesis, Isolation and Application of Carbohydrates)
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