Advanced Biopolymers for Tissue Engineering Application
A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biobased and Biodegradable Polymers".
Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 6970
Special Issue Editor
Interests: biodegradable polymers; polysaccharides; chitosan; bio-based polymeric materials; hydrogels; tissue engineering and regeneration; drug delivery systems
Special Issue Information
Dear Colleagues,
Tissue engineering can solve many problems of regenerative medicine, with the capacity to improve the duration and quality of human life by restoring the lost structure and function of organs and tissues. The main task of tissue engineering and regenerative medicine is to develop an optimal biodegradable polymer scaffold (matrix), ensuring cell adhesion and proliferation. This must be gradually replaced by forming tissues or organs. The main requirements that are imposed on polymer scaffolds are biological compatibility, a large porous structure that supports migration and settlement (adhesion) while boosting cell life, and a complex of mechanical and physicochemical properties (elasticity, atraumaticity, water swelling ability, adhesion characteristics). The matrix should resorb in the body after performing the function of a temporary framework that supports the growth and proliferation of cells and the formation of new tissues based on it. Therefore, biodegradable polymers are used as biomaterials to create scaffolds, and the choice of polymer is determined by its biomechanical compatibility with the resorbed tissue. Materials used in soft tissue replacement surgery should have a high water-retaining capacity. Therefore, from the point of view of biomimetics, the use of polysaccharide hydrogels is preferable over hydrophobic biodegradable polyesters. Conversely, due to their mechanical strength and osteoconductive properties, composite materials based on polyhydroxyalkanoates and inorganic phosphates are considered promising for bone replacement. High porosity and the required pore size in scaffolds are the main conditions for ensuring cell colonization and proliferation, and now various advanced technologies are adopting to build porous scaffolds for regenerating organs and tissues for suitable application in the tissue engineering.
The Special Issue, entitled “Advanced Biopolymers Application in Tissue Engineering”, aims to provide a platform for the communication and fast publication of high-quality original and review papers These should span topics like the development of biopolymer scaffolds, hydrogels, polymer-based composites, and formation methods of porous structures.
The scope of this Special Issue includes, but is not limited to, the following topics:
- Biopolymers for tissue engineering and regeneration (chitin, chitosan, fibroin, collagens polylactic acid, polyhydroxyalkanoates and so on);
- Bio-based polymeric materials: polysaccharide hydrogels, composites and hybrid materials;
- Formation methods of biopolymer matrices porous structures such as cryotropic gelation and 3D printing;
- The relationship in biopolymeric scaffold between "structure-morphology" and "morphology-properties";
- New technologies of forming biomaterials for tissue engineering;
- Biopolymer-based drug delivery systems in regenerative medicine;
- Methods for evaluating biocompatibility and effectiveness of application as an artificial matrix for tissue engineering of bio-based polymer materials.
Prof. Dr. Nataliya Kildeeva
Guest Editor
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- biodegradable polymers
- biomaterials
- bio-based composites
- drug delivery
- hydrogels
- scaffolds
- tissue engineering
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