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Recent Advances in Chitosan and Its Applications

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biobased and Biodegradable Polymers".

Deadline for manuscript submissions: 31 October 2026 | Viewed by 1610

Special Issue Editors


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Guest Editor
Centro Tecnológico de Ciências Exatas e Educação (CTE), Universidade Federal de Santa Catarina, Rua Engenheiro Udo Deeke, 485, Blumenau 89065-100, SC, Brazil
Interests: biodegradable polymers; polymer nanocomposites; nanoparticles functionalization; functional materials; encapsulation; active packaging

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Guest Editor
Centro Tecnológico de Ciências Exatas e Educação (CTE), Universidade Federal de Santa Catarina, Rua Engenheiro Udo Deeke, 485, Blumenau 89065-100, SC, Brazil
Interests: biomaterials; nanocomposites; chitosan; SPIONs; magnetic materials

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Guest Editor
Área do Conhecimento de Ciências Exatas e Engenharias, Universidade de Caxias do Sul, Rua Francisco Getúlio Vargas, 1130, Caxias do Sul 95070-560, RS, Brazil
Interests: chitosan; PVA; green synthesis; nanoparticles; wastewater treatment; adsorption

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Guest Editor
Instituto de Química, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9500, Porto Alegre 91501-970, RS, Brazil
Interests: biopolymers; nanocomposites; polymer characterization; polymer synthesis; smart polymers; sustainability

Special Issue Information

Dear Colleagues,

The growing demand for sustainable solutions has driven increasing interest in renewable and biodegradable materials. Among these, chitosan has emerged as a particularly promising candidate due to its superior and versatile properties compared to other biopolymers. Chitosan is obtained from chitin, the second most abundant natural polymer after cellulose, which is primarily found in the exoskeleton of crustaceans, insect cuticles, and the cell walls of fungi and yeast.

In addition to its intrinsic properties, such as renewability, antimicrobial activity, biodegradability, biocompatibility, hydrophilicity, and high adsorption capacity, chitosan has attracted particular attention as a versatile material due to its relatively low cost and the presence of characteristic functional groups in its structure. The amino and hydroxyl functional groups provide active sites that enhance solubility, enable chemical modifications, and improve adsorption capacity and catalyst immobilization, among others. Chitosan can be processed into diverse material forms, such as hydrogels, fibers, nanostructures, films, and coating, and has been extensively investigated across numerous fields, including pharmaceuticals, medicine, veterinary medicine, food technology, chemistry, energy, textiles, photocatalysis, and agriculture.

The aim of this Special Issue is to highlight the most recent advances in chitosan-based materials and to explore their current and potential applications in the fields mentioned above and beyond.

Prof. Dr. Larissa Nardini Carli
Prof. Dr. Cristiano da Silva Teixeira
Prof. Dr. Marcelo Giovanela
Prof. Dr. Tales da Silva Daitx
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chitosan
  • hydrogels
  • films
  • coatings
  • fibers
  • nanostructures
  • biomaterials
  • scaffolds
  • formulations

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Published Papers (1 paper)

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Review

28 pages, 3759 KB  
Review
Chitosan-Nanoencapsulated Curcumin for the Treatment of Diabetic Foot Ulcers: A Review
by Laura Andrea Gómez-de la Cruz, Juan David Rodríguez Macías and Carlos David Grande-Tovar
Polymers 2026, 18(4), 511; https://doi.org/10.3390/polym18040511 - 19 Feb 2026
Viewed by 1264
Abstract
Diabetic foot ulcers (DFUs) are wounds characterized by chronic inflammation and elevated oxidative stress that delay tissue regeneration and render them susceptible to infection, thereby complicating healing. Therefore, treating DFUs effectively is often challenging and requires a combined approach that integrates anti-inflammatory, antioxidant, [...] Read more.
Diabetic foot ulcers (DFUs) are wounds characterized by chronic inflammation and elevated oxidative stress that delay tissue regeneration and render them susceptible to infection, thereby complicating healing. Therefore, treating DFUs effectively is often challenging and requires a combined approach that integrates anti-inflammatory, antioxidant, and antibacterial effects. Curcumin, a widely studied natural compound, has shown promise in wound healing by modulating inflammation, oxidative stress, and infections. However, its bioavailability, absorption, and solubility issues limit its clinical applications. To overcome these limitations, curcumin has been incorporated into nanosystems, such as hydrogels, nanofibers, nanoparticles, vesicles, and micelles, thereby improving its delivery and enabling efficient local administration. Among these nanosystems, those formulated with chitosan are of particular interest due to chitosan’s intrinsic wound-healing properties. For that reason, this review comprehensively analyzes the literature on the therapeutic mechanisms of the chitosan–curcumin system for diabetic wound closure and compares them with those of free curcumin. The results show that this system exerts anti-inflammatory, antioxidant, and antimicrobial effects through specific mechanisms, including macrophage polarization, modulation of oxidative stress, and alteration of bacterial cell walls. In addition, significant improvements are observed in key healing processes, including cell migration, fibroblast proliferation, collagen deposition, and re-epithelialization. It should be noted that chitosan not only promotes curcumin release but also contributes to its therapeutic effect through its inherent antimicrobial and hemostatic properties, reinforcing its potential as a comprehensive strategy for the treatment of DFUs. Full article
(This article belongs to the Special Issue Recent Advances in Chitosan and Its Applications)
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