Plants as Molecular Farming Factories
A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Plant Molecular Biology".
Deadline for manuscript submissions: closed (20 July 2023) | Viewed by 8886
Special Issue Editors
Interests: plant physiology; molecular farming; gene editing; CRISPR; genetic engineering
Interests: plant biotechnology; molecular farming; plant secondary metabolism; in vitro plant cell culture
Special Issue Information
Dear Colleagues,
Molecular Farming is the production of different molecules for the pharmaceutical and chemical industries in transgenic organisms and is achieved through genetic manipulation; however, it is mainly used to describe the production of recombinant proteins in plants. Some of the advantages of the production of recombinant proteins in plants are aspects related to biosecurity since plants do not produce toxins, as bacteria do, nor bear pathogens for humans and animals, as animal cells do. Additionally, plants are able to produce complex glycoproteins and folding in the same way that mammal cells are. Finally, the transient production and the in vitro culture platform are valuable tools that have previously demonstrated their utility to increase recombinant protein yields. Due to the COVID-19 pandemic, molecular farming has demonstrated its relevance in the field of recombinant vaccine production. The bioproduction of recombinant pharmaceuticals in plant systems is becoming a promising alternative to existing platforms that are based on mammalian or bacterial cells. The cultivation of plant cells under the controlled conditions of bioreactors ensures the production of high-quality proteins that are in accordance with GMP (Good Manufacturing Practice) standards. This Special Issue of Plants will include articles discussing the most recent novelties that are related to this promising area.
Prof. Dr. Elena Victorovna Deineko
Prof. Dr. María Alejandra Alvarez
Guest Editors
Manuscript Submission Information
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Keywords
- molecular farming
- plant expression systems
- transgenic plants
- bioreactors
- recombinant proteins
- biopharmaceuticals
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