Drug–Drug Interactions

Dear Colleagues,

Drug–drug interactions (DDIs) cause one drug to affect other drugs, leading to a reduced drug efficacy or an increased toxicity of the affected drugs. In some cases, drug interactions are reported to cause severe adverse drug reactions that are life-threatening to the patient. Traditionally, DDIs have been evaluated around the selective action of drugs on specific CYP enzymes. The interaction of drugs based on CYPs is still very important for drug interactions, but recently, other important mechanisms have also been studied as contributing to the drug interactions, such as drug transporter- or UDP-glucuronyltransferase-mediated DDI. In addition, the novel mechanism to regulate DDI can also be suggested. In the case of the substance to be interacted, not only the DDI, but also the herb– or food–drug interactions have been reported to be clinically relevant in terms of adverse side effects. Reporting examples of drug interactions on a marketed drug or a new mechanism study will be very helpful for preventing the side effects of the patient taking them. This Special Issue has the aim of highlighting the current progress in the clinical or non-clinical interactions of commercial drugs and the elucidation of the mechanism of drug interactions.

Prof. Dong Hyun Kim
Prof. Sangkyu Lee
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.