Novel Biopolymer for Targeted Drug Therapy

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".

Deadline for manuscript submissions: closed (20 April 2024) | Viewed by 2108

Special Issue Editors


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Guest Editor
School of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT, UK
Interests: physicochemical and biological properties of water-soluble biopolymers derived from biomass (e.g., plants, seaweeds, and bacteria) and food waste; development of soft nanostructured biomaterials obtained by physical, chemical or enzymatic methods (e.g., hydrogels, polyelectrolyte complexes, colloidal micro- and nanoparticles, and emulsions); mechanistic aspects of interaction of these biomaterials with biological systems (epithelia, mucosa, bacteria, and biofilms); colloidal nanoparticles for drug and gene delivery and for antibacterial targeting; association and release of bioactive compounds relevant to food and pharmacy
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Guest Editor
Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, Italy
Interests: drug; drug delivery; biological samples; sample treatment; targeted therapy; liquid chromatography; mass spectrometry; supramolecular solvents; antioxydants

Special Issue Information

Dear Colleagues,

Smart drug delivery biosystems with performed therapeutic efficacy within optimal patient compliance and cost effectiveness have been explored. Biodegradable polymers have been widely employed in the clinical delivery industry because they can be biologically broken down inside the human body, releasing non-toxic components. Tailored biocompatible drug delivery benefits from a comprehensive understanding of biopolymers features, which involve extraction manufacturing techniques, chemistry, and studies of surface properties, rheology, and biodegradability.

This Special Issue will focus on “Novel Biopolymer for Targeted Drug Therapy”. Original research papers and comprehensive reviews are welcomed.

Prof. Dr. Francisco M. Goycoolea
Dr. Francesca Accioni
Guest Editors

Manuscript Submission Information

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Keywords

  • biopolymer
  • targeted therapy
  • biomaterials
  • bioactivity
  • microparticles
  • nanoparticles
  • nanocomposites
  • hydrogel
  • drug delivery

Published Papers (1 paper)

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Review

25 pages, 1330 KiB  
Review
Nanomaterial-Based Drug Delivery Systems for Ischemic Stroke
by Chengting Jiang, Yang Zhou, Rong Chen, Mengjia Yang, Haimei Zhou, Zhengxiu Tang, Hongling Shi and Dongdong Qin
Pharmaceutics 2023, 15(12), 2669; https://doi.org/10.3390/pharmaceutics15122669 - 24 Nov 2023
Viewed by 1559
Abstract
Ischemic stroke is a leading cause of death and disability in the world. At present, reperfusion therapy and neuroprotective therapy, as guidelines for identifying effective and adjuvant treatment methods, are limited by treatment time windows, drug bioavailability, and side effects. Nanomaterial-based drug delivery [...] Read more.
Ischemic stroke is a leading cause of death and disability in the world. At present, reperfusion therapy and neuroprotective therapy, as guidelines for identifying effective and adjuvant treatment methods, are limited by treatment time windows, drug bioavailability, and side effects. Nanomaterial-based drug delivery systems have the characteristics of extending half-life, increasing bioavailability, targeting drug delivery, controllable drug release, and low toxicity, thus being used in the treatment of ischemic stroke to increase the therapeutic effects of drugs. Therefore, this review provides a comprehensive overview of nanomaterial-based drug delivery systems from nanocarriers, targeting ligands and stimulus factors of drug release, aiming to find the best combination of nanomaterial-based drug delivery systems for ischemic stroke. Finally, future research areas on nanomaterial-based drug delivery systems in ischemic stroke and the implications of the current knowledge for the development of novel treatment for ischemic stroke were identified. Full article
(This article belongs to the Special Issue Novel Biopolymer for Targeted Drug Therapy)
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