Nanostructured Therapeutics and Diagnostic Platforms for Tumor Microenvironment Modulation and Precision Cancer Therapy
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: 31 October 2026 | Viewed by 168
Special Issue Editors
Interests: pharmaceutical technology; nanotechnology; gene delivery; liposomes, nanocarrier development and characterization; data science
Special Issues, Collections and Topics in MDPI journals
Interests: nanotechnology; liposomes; nanoemulsion; model lipid membranes; drug targeting
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer therapy is significantly affected by the complex tumor microenvironment (TME), which affects tumor growth, metastasis, and drug response, as well as drug resistance. Therefore, achieving effective cancer treatment requires strategies that not only concern cancer cell targeting but also modulate this dynamic and multifaceted microenvironment characterized by dense extracellular matrix, hypoxia, acidity, and immunosuppression. In this context, nanostructured platforms offer a powerful tool that can be precisely engineered to overcome biological barriers, enable targeted delivery, and responsiveness to stimuli for drug release. Moreover, they can perform immune reprogramming and real-time imaging, integrating both therapeutic and diagnostic functions. This Special Issue aims to highlight emerging concepts and recent advances in TME modulation that employ advanced nanostructured systems and ultimately contribute to personalized and effective cancer diagnosis and treatment. We invite contributions that define the next generation of precision oncology, from smart nanoparticles to advanced imaging probes, with strong potential for clinical translation.
Dr. Elena Mourelatou
Dr. Sophia Hatziantoniou
Guest Editors
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Keywords
- nanomedicine
- tumor microenvironment (TME) modulation
- precision oncology
- targeted drug delivery
- theranostics
- stimuli-responsive nanocarriers
- cancer immunotherapy
- molecular imaging
- tumor stromal modulation
- immune reprogramming
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