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Special Issue "Mosquito-Borne Diseases: Novel Control Strategies"
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Parasitic Pathogens".
Deadline for manuscript submissions: closed (28 February 2022) | Viewed by 13477
Special Issue Editors
Interests: mosquito-pathogen interaction; mosquito genome editing and transgenics; vector biology and control
Interests: mosquito control; mosquito metabolism and immunity; mosquito-associated bacteria; Wolbachia
Special Issue Information
Mosquito-borne diseases are caused by parasites, viruses, or bacteria and spread by mosquitoes, particularly those from the genera Aedes, Anopheles, and Culex. Key mosquito-transmitted pathogens that cause disease in humans include Plasmodium parasites, which cause malaria, dengue virus, West Nile virus, Chikungunya virus, and Zika virus. More than half of the world’s population lives in areas with a high risk of transmission, and it is estimated that these diseases cause more than one million deaths each year.
In the absence of effective vaccines or medical treatments, controlling mosquito populations is the most common strategy to limit the transmission of these diseases, and is typically approached through the use of insecticides, or larval source reduction. However, the declining efficacy of commonly-used insecticides, and the recent emergence and re-emergence of arboviruses like Zika and Chikungunya have highlighted the challenges involved with effectively controlling these diseases using only the historical techniques.
Fortunately, recent advances in mosquito science have spurred the development of many promising approaches to controlling mosquitoes and the diseases they transmit. These include, but are not limited to the following: gene drive-based tools for mosquito population replacement or suppression, tools for efficiently generating transgenic mosquitoes that are more resistant or even refractory to key pathogens, innovative strategies for human vaccine design against mosquito-transmitted pathogens, the growing use of Wolbachia as an agent for replacing or suppressing mosquito populations, the identification and development of new biopesticides, including those based on RNAi technologies, and the optimization of the sterile insect technique.
These new approaches to controlling mosquito-transmitted diseases offer unique opportunities to reduce logistical costs associated with mosquito control, to reduce spillover ecological impacts associated with chemical insecticides, and to reduce the risk of genetic resistance to common insecticides, and, most importantly, to reduce disease incidence. At the same time, there are inherent challenges to navigate, including regulatory uncertainty, distinct or unpredicted ecological, ethical, and social impacts, and requirements for stakeholder engagement and education.
This Special Issue will highlight some of the different, emerging approaches to controlling mosquito-transmitted diseases, from those still in the early stages of laboratory testing, to those already in semi-field or field trials. We are particularly interested in research on approaches with sustainable and/or environmental-friendly prospects, in studies that bridge the gap between basic and translational science, and studies that offer a framework for developing and employing new mosquito-control tools.
Dr. Shengzhang Dong
Dr. Eric Caragata
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- mosquito control
- gene drive
- genetically modified mosquitoes