Special Issue "Q Fever"

A special issue of Pathogens (ISSN 2076-0817).

Deadline for manuscript submissions: 31 August 2020.

Special Issue Editor

Dr. Eric Ghigo
Guest Editor
IHU-Méditerranée Infection, Marseille, France
Interests: Transmissible diseases and tropical pathologies; Lipopolysaccharide; Q fever; Coxiella burnetii; Phagosome; Planarians; Evolution; Antibacterial response

Special Issue Information

Dear Colleagues,

Query fever so called Q fever is caused by Coxiella burnetii, a gram negative bacteria. The Q fever, is a zoonosis characterized by a lethal endocarditis. Because of its virulence Coxiella burnetii is considered as potential biowarfare and bioterrorism agent. Coxiella burnetii infect a wide range of animals and is an intracellular bacteria that replicates within a membrane-bound compartment. The introduction of the axenic culture of Coxiella burnetii allowed a better characterization of this pathogen. Because of the The genetic analysis of the various strain of Coxiella burnetii, the of virulence determinants are now better known as well the molecular variations in lipopolysaccharide a major outer membrane component, of Coxiella burnetii. The Q fever has a worldwide distribution, the immune response engage by the host during the Q fever is now well characterized, however is interestingly to note that the last epidemic outbreaks unravelled that the epidemiological features of the Q fever vary according to the geographic.

This special issue aims to take stock of the latest advances in research on Q fever and its agent, Coxiella burnetii, from a microbiological, clinical, genetic and immunological point of view, as well as from a cell biology point of view.

Dr. Eric Ghigo
Guest Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Q fever
  • C. burnetii
  • Vectors
  • Phagosome
  • Immunity
  • Genomic
  • Epidemiology
  • Microbiology
  • Clinical

Published Papers (1 paper)

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Open AccessBrief Report
New Genotypes of Coxiella burnetii Circulating in Brazil and Argentina
Pathogens 2020, 9(1), 30; https://doi.org/10.3390/pathogens9010030 - 28 Dec 2019
Coxiella burnetii, the zoonotic agent of Q fever, has a worldwide distribution. Despite the vast information about the circulating genotypes in Europe and North America, there is a lack of data regarding C. burnetii strains in South America. Here, we show the [...] Read more.
Coxiella burnetii, the zoonotic agent of Q fever, has a worldwide distribution. Despite the vast information about the circulating genotypes in Europe and North America, there is a lack of data regarding C. burnetii strains in South America. Here, we show the presence of novel multispacer sequence typing (MST) genotypes of C. burnetii in two clusters detected in Brazil and Argentina that seem to be distant in parenthood. Argentinian strains isolated from a tick belongs to a new phylogenetic branch of C. burnetii, and the Brazilians strains may be related to MST 20 and 61. Multilocus variable number tandem repeats analysis (MLVA) typing provided a deeper resolution that may be related to host clusters of bovines, caprine, ovine, and ticks. Our results corroborate with the reports of geotypes of C. burnetii. Thus, we highlight the need for more genotyping studies to understand the genetic diversity of C. burnetii in South America and to confirm the hypothesis of host-related genotypes. We also emphasize the importance of virulence studies for a better understanding of Q fever in the region, which may help in surveillance and disease prevention programs. Full article
(This article belongs to the Special Issue Q Fever)
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Performance evaluation and validation of air samplers to detect aerosolized Coxiella burnetii

By Hasanthi Abeykoon et.al

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