Special Issue "Phage Therapy in Aquaculture: Current Developments and Future Challenges"
A special issue of Pathogens (ISSN 2076-0817).
Deadline for manuscript submissions: closed (1 March 2022) | Viewed by 5594
2. Aquatic Biologicals, Thalassocosmos, Former American Base of Gournes, Heraklion, Crete, Greece
Interests: fish diseases; phage microbiology and phage therapy; vaccine development; disease prevention in aquaculture
Aquaculture is the fastest growing sector of animal production worldwide. Very soon, most fishery products will come from aquaculture than from traditional fisheries. Intensification of aquaculture leads to an increase of disease outbreaks. When it comes to bacterial infections, administration of antibiotics is the first line of defense for the fish producer. Rational use of antibiotics is common practice in all animal production sectors; nevertheless, the emergence of antimicrobial resistance as one of the most significant threats for humanity has created an urgent need to replace antibiotics with more sustainable, alternative methods. Phage therapy is one of the most promising alternatives, and there is a steadily increasing volume of scientific publications towards this direction.
Phage research for aquaculture applications is currently being practiced in several parts of the world, including Europe, Asia, America, and Oceania. New phages with potency against fish and shellfish pathogens are continuously described, and new information is added to the scientific literature every day. However, there are many gaps in significant aspects before we can see the successful transition of phage therapy from the lab to the actual aquaculture production. These include stability of phages in the aquaculture environment, resistance development, upscaling of production, quality of the product, integration of modern approaches such as phage engineering, and of course regulation of phage therapy.
These are the main issues that we aspire to cover through this Special Issue of the journal Pathogens. The scope of the issue also includes current developments in phage research in relation to aquaculture (e.g., the role of prophages in virulence of aquaculture pathogens), discovery of new phages against aquaculture pathogens, and trials and applications in live feeds, fish, and invertebrates. We would like to encourage the submission of papers dealing with the use of phage lytic enzymes, the use of phages as probiotics or in combination with probiotics, and the role of phages in the intestinal environment of fish.
Both original research and review articles are welcomed.
Dr. Pantelis Katharios
Prof. Roberto Bastías
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- phage microbiology
- phage therapy
- antibiotic resistance
- phage genomics