Disrupting Bacterial Biofilms: Recent Progress and Novel Strategies to Address Persistent Infections
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Bacterial Pathogens".
Deadline for manuscript submissions: 31 October 2026 | Viewed by 287
Editors
Interests: biofilms; resistance; healthcare-associated infections; antibiotics
Special Issue Information
Dear Colleagues,
Biofilm production represents a critical survival strategy for many microorganisms and has emerged as a central topic in modern microbiology and clinical research. This mode of growth is closely associated with persistent and chronic infections, as biofilms confer a markedly increased tolerance to antimicrobial agents and disinfectants compared with planktonic cells. Consequently, biofilm-associated infections are particularly difficult to eradicate, often leading to treatment failure, recurrence and increased healthcare burden, underscoring the urgent need for deeper understanding and innovative therapeutic approaches.
We are pleased to invite you to contribute a manuscript to the Special Issue titled “Disrupting Bacterial Biofilms: Recent Progress and Novel Strategies to Address Persistent Infections”.
This Special Issue addresses screening strategies and explores the therapeutic challenges and clinical limitations associated with biofilm formation in infectious diseases.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:
- Biofilm-associated antimicrobial tolerance and resistance
- Novel antibiofilm agents and therapeutic compounds
- Quorum sensing and its disruption as an antibiofilm strategy
- Host–biofilm interactions in persistent infections
- Biofilms in chronic and device-associated infections
- Innovative drug delivery systems targeting biofilms
- Combination therapies against biofilm-related infections
- Emerging in vitro and in vivo models for biofilm research
We look forward to receiving your contributions.
Dr. Adrián Martinez-Melendez
Dr. Flora Eduarda Cruz-López
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- biofilms
- resistance
- healthcare-associated infections
- antibiotics
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