Neglected Parasitic Diseases: Epidemiology, Pathobiology, and Innovative Control

Dear Colleagues,

Neglected parasitic diseases (NPDs) remain a persistent and often underestimated global health challenge, disproportionately affecting impoverished and marginalized populations. Despite decades of research and intervention, millions continue to suffer from parasitic infections such as schistosomiasis, leishmaniasis, soil-transmitted helminthiases, filariasis, and other zoonotic and protozoan diseases that receive limited scientific and policy attention. Recent advances in molecular biology, epidemiological modelling, data analytics, and One Health frameworks have opened new pathways for understanding and controlling these diseases. At the same time, climate change, urbanization, and socio-economic inequalities are reshaping their distribution and transmission dynamics. Despite progress in control, limited attention, weak surveillance, and emerging resistance hinder elimination efforts.

Topics include disease mapping, climate and environmental impacts, host–parasite interactions, molecular and omics-based insights, drug and vaccine development, and One Health-based control approaches. We also welcome papers addressing socioeconomic, policy, and implementation challenges, including digital tools, surveillance innovations, and community-based interventions. Our goal is to advance multidisciplinary collaboration linking human, animal, and environmental health, and to highlight scalable, data-driven strategies for sustainable control and elimination. This Special Issue seeks to bring together cutting-edge research, reviews, and perspectives that address the epidemiological trends, pathobiological mechanisms, and innovative strategies for control and elimination of neglected parasitic diseases.

Dr. Kumar Sachin Singh
Dr. Nikhilesh Joardar
Guest Editors

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