Rodent-Borne Viruses and Diseases

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Viral Pathogens".

Deadline for manuscript submissions: closed (1 December 2023) | Viewed by 2077

Special Issue Editors


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Guest Editor
Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-900, Brazil
Interests: arenavirus; rodent-borne diseases; viral hemorrhagic fevers
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-900, Brazil
Interests: hantavirus; rodent-borne diseases; hantavirus pulmonary syndrome
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Rodents are the most diverse order of mammals, showing a distinct life history trait, and serve as important reservoirs for many pathogens, with or without zoonotic potential. Rodent-borne viruses are a heterogenous group of viruses associated with different species of rodents. In the last few years, many distinct species of rodent-associated viruses have been recognized in other taxa of hosts, including bats, fishes, snakes, and other reptiles. Attention has been directed toward those related to human disease worldwide, mainly to members of the Arenaviridae and Hantaviridae families, responsible for significant morbidity and mortality. However, a wide range of other rodent-associated viruses, including members of the Poxiviridae family, hepatitis E virus, flaviviruses, coronaviruses, encephalomyocarditis virus, influenza A virus and others, are of increasing importance for researchers in the field.

This Special Issue aims to cover the whole spectrum of research focused on rodent-borne viruses detected not only in rodents but in other host species. We welcome but are not restricted to eco-epidemiological studies; descriptions of new viruses; studies on virus–host interactions; studies on the ecological processes involved in virus diversity and host adaptation; studies on the evolutionary processes in viruses and rodents and other animal reservoirs; and research on the spillover from infected animal species to humans and animal models for studying rodent-borne viruses. 

Dr. Jorlan Fernandes
Dr. Renata Carvalho De Oliveira
Guest Editors

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Keywords

  • rodent-borne viruses
  • Hantaviridae
  • Arenaviridae
  • Poxviridae
  • zoonosis

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Published Papers (1 paper)

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Research

12 pages, 1697 KiB  
Article
Identification of a Novel Hepacivirus in Southeast Asian Shrew (Crocidura fuliginosa) from Yunnan Province, China
by Ling Guo, Bei Li, Peiyu Han, Na Dong, Yan Zhu, Fuli Li, Haorui Si, Zhengli Shi, Bo Wang, Xinglou Yang and Yunzhi Zhang
Pathogens 2023, 12(12), 1400; https://doi.org/10.3390/pathogens12121400 - 28 Nov 2023
Cited by 3 | Viewed by 1707
Abstract
The genus Hepacivirus contains single-stranded positive-sense RNA viruses belonging to the family Flaviviridae, which comprises 14 species. These 14 hepaciviruses have been found in different mammals, such as primates, dogs, bats, and rodents. To date, Hepacivirus has not been reported in the [...] Read more.
The genus Hepacivirus contains single-stranded positive-sense RNA viruses belonging to the family Flaviviridae, which comprises 14 species. These 14 hepaciviruses have been found in different mammals, such as primates, dogs, bats, and rodents. To date, Hepacivirus has not been reported in the shrew genus of Crocidura. To study the prevalence and genetic evolution of Hepacivirus in small mammals in Yunnan Province, China, molecular detection of Hepacivirus in small mammals from Yunnan Province during 2016 and 2017 was performed using reverse-transcription polymerase chain reaction (RT-PCR). Our results showed that the overall infection rate of Hepacivirus in small mammals was 0.12% (2/1602), and the host animal was the Southeast Asian shrew (Crocidura fuliginosa) (12.5%, 2/16). Quantitative real-time PCR showed that Hepacivirus had the highest viral RNA copy number in the liver. Phylogenetic analysis revealed that the hepaciviruses obtained in this study does not belong to any designated species of hepaciviruses and forms an independent clade. To conclude, a novel hepacivirus was identified for the first time in C. fuliginosa specimens from Yunnan Province, China. This study expands the host range and viral diversity of hepaciviruses. Full article
(This article belongs to the Special Issue Rodent-Borne Viruses and Diseases)
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