Calcium Across the Life Cycle: A Pivotal Role in Aging and Age-Related Diseases
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Immunology".
Deadline for manuscript submissions: 5 January 2026 | Viewed by 2550
Special Issue Editors
Interests: calcium; vitamin D; metabolic bone diseases; osteoporosis; atherosclerosis; fragility fractures; sarcopenia; aging
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Calcium is a key nutrient in the human body. The primary emphasis on calcium consumption during its initial scientific discovery was focused on early human life, primarily during growth periods of infancy and childhood. Nowadays, interest in calcium metabolism and requirements have been expanded to apply to the entire life cycle from birth through the oldest decades of life. Many commercial foods and nutritional supplement products contain calcium fortifications due to there being a wider audience for them. The purpose of this Special Issue is (a) to examine the role of calcium in human health and aging from cellular to clinical levels, (b) to review relationships between calcium levels or intake and physiopathological pathways involving the body’s homeostasis, (c) to summarize the evidence about calcium metabolism and multisystemic age-related chronic diseases, (d) to compare nutrient requirements for calcium across life cycle groups and global populations, and (e) to discuss strategies to address diet deficiencies or assure optimal calcium metabolism over the life cycle.
Prof. Dr. Stefano Gonnelli
Prof. Dr. Carmelinda Ruggiero
Guest Editors
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Keywords
- calcium signaling
- aging and age-related diseases
- neuro-degenerative diseases
- cardiovascular diseases
- cancer
- osteoporosis
- sarcopenia
- bone–muscle unit
- immune system
- immuno-modulation
- cellular senescence
- hallmarks of aging
- vitamin D
- parathyroid hormone
- lactose intolerance
- dietary requirements
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