Modulation of the Intestinal Microbiome in Chronic Diseases: Mechanisms, Nutritional Interventions, and Clinical Implications
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Prebiotics, Probiotics and Postbiotics".
Deadline for manuscript submissions: 15 October 2026 | Viewed by 58
Special Issue Editor
Interests: intestinal microbiome; gut dysbiosis; chronic diseases; probiotics; prebiotics; postbiotics; microbiota modulation; host–microbiome interactions; metabolic disorders
Special Issue Information
Dear Colleagues,
The intestinal microbiome plays a fundamental role in regulating host metabolism, immune function, and overall health. In recent years, a growing body of evidence has demonstrated that disruptions in gut microbial balance—commonly referred to as dysbiosis—are closely associated with the development and progression of numerous chronic diseases, including metabolic disorders, gastrointestinal conditions, cardiovascular diseases, and neurological pathologies. Consequently, strategies aimed at modulating the intestinal microbiome have attracted increasing attention as promising approaches for disease prevention and therapeutic intervention.
This Special Issue seeks to explore recent advances in understanding the mechanisms linking gut microbiota to the pathophysiology of chronic diseases, while also highlighting innovative approaches for microbiome modulation. Particular emphasis will be placed on the potential roles of prebiotics, probiotics, postbiotics, dietary interventions, and microbiota-targeted nutritional therapies in restoring microbial balance and promoting host health. Submissions focusing on molecular pathways, host–microbiome interactions, translational research, and clinical evidence are especially encouraged.
By bringing together original research articles and comprehensive review papers, this Special Issue aims to provide an updated overview of microbiome-centered strategies and their potential contribution to the prevention and management of chronic diseases.
Dr. Maria Adriana Neag
Guest Editor
Manuscript Submission Information
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Keywords
- intestinal microbiome
- gut dysbiosis
- chronic diseases
- probiotics
- prebiotics
- postbiotics
- microbiota modulation
- host–microbiome interactions
- metabolic disorders
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