Special Issue "Marine Omega-3s and Human Health"

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Micronutrients and Human Health".

Deadline for manuscript submissions: 30 December 2020.

Special Issue Editor

Dr. James DiNicolantonio
Website
Guest Editor
Preventive Cardiology, St. Luke's Hospital, Kansas City, 816, 975 MO, USA
Interests: omega-3; magnesium; nutraceuticals; nutrition

Special Issue Information

Dear Colleagues,

In this Special Issue of Nutrients, we would like to bring together papers dealing with topics relating to marine omega-3s (EPA/DHA) on health conditions including but not limited to cardiovascular, metabolic, and mental health. We welcome all types of papers, ranging from review articles, meta-analyses, to original data articles pertaining to long-chain ‘marine’ omega-3s.

The beneficial effects of marine omega-3s have been a topic of hot debate for decades. Many clinicians and the general public are confused about whether these long-chain fatty acids provide any benefits. There is also confusion regarding what health conditions may be improved with omega-3 consumption, what dose of EPA/DHA is needed for improving health markers, and whether there is a difference between many common over the counter omega-3 supplements and prescription omega-3s. This issue will help to answer some of these questions and provide further evidence for additional research that may be needed in the marine omega-3 space.

Therefore, the journal aims to collect high-quality manuscripts that focus on marine omega-3s effects on health conditions.

Dr. James DiNicolantonio
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Omega-3
  • Eicosapentaenoic acid
  • Docosahexaenoic acid
  • Fish oil

Published Papers (2 papers)

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Research

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Open AccessArticle
Effects of Omega-3 Polyunsaturated Fatty Acid Supplementation on Non-Alcoholic Fatty Liver: A Systematic Review and Meta-Analysis
Nutrients 2020, 12(9), 2769; https://doi.org/10.3390/nu12092769 - 11 Sep 2020
Cited by 1
Abstract
(1) Aim: Non-alcoholic fatty liver disease (NAFLD) is a prevalent disease worldwide. Omega-3 polyunsaturated fatty acids (n-3 PUFAs) bear anti-inflammatory action and can ameliorate hyperlipidemia. We wish to appraise the effects of n-3 PUFAs supplement on NAFLD. (2) Methods: We searched CENTRAL, Embase, [...] Read more.
(1) Aim: Non-alcoholic fatty liver disease (NAFLD) is a prevalent disease worldwide. Omega-3 polyunsaturated fatty acids (n-3 PUFAs) bear anti-inflammatory action and can ameliorate hyperlipidemia. We wish to appraise the effects of n-3 PUFAs supplement on NAFLD. (2) Methods: We searched CENTRAL, Embase, and MEDLINE on 29 March 2020 for randomized control trials (RCTs) on the effects of n-3 PUFAs supplementation in treating NAFLD. The Cochrane Collaboration’s tool was used to assess the risk of bias of included RCTs. (3) Results: We included 22 RCTs with 1366 participants. The risk of bias of included RCTs was generally low or unclear. n-3 PUFAs supplementation significantly reduced liver fat compared with placebo (pooled risk ratio 1.52; 95% confidence interval (CI) 1.09 to 2.13). n-3 PUFAs supplementation also significantly improved the levels of triglyceride, total cholesterol, high-density lipoprotein, and body-mass index, with pooled mean difference and 95% CI being −28.57 (−40.81 to −16.33), −7.82 (−14.86 to −0.79), 3.55 (1.38 to 5.73), and −0.46 (−0.84 to −0.08), respectively. (4) Conclusions: The current evidence supports the effects of n-3 PUFAs supplementation in improving fatty liver. n-3 PUFAs supplementation may also improve blood lipid levels and obesity. Full article
(This article belongs to the Special Issue Marine Omega-3s and Human Health)
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Review

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Open AccessReview
The Importance of Marine Omega-3s for Brain Development and the Prevention and Treatment of Behavior, Mood, and Other Brain Disorders
Nutrients 2020, 12(8), 2333; https://doi.org/10.3390/nu12082333 - 04 Aug 2020
Cited by 1
Abstract
Most of the global population is deficient in long-chain marine omega-3s. In particular, docosahexaenoic acid (DHA), a long-chain omega-3 fatty acid, is important for brain and eye development. Additionally, DHA plays a significant role in mental health throughout early childhood and even into [...] Read more.
Most of the global population is deficient in long-chain marine omega-3s. In particular, docosahexaenoic acid (DHA), a long-chain omega-3 fatty acid, is important for brain and eye development. Additionally, DHA plays a significant role in mental health throughout early childhood and even into adulthood. In the brain, DHA is important for cellular membrane fluidity, function and neurotransmitter release. Evidence indicates that a low intake of marine omega-3s increases the risk for numerous mental health issues, including Attention Deficit Hyperactivity Disorder (ADHD), autism, bipolar disorder, depression and suicidal ideation. Studies giving supplemental marine omega-3s have shown promise for improving numerous mental health conditions. This paper will review the evidence surrounding marine omega-3s and mental health conditions. Full article
(This article belongs to the Special Issue Marine Omega-3s and Human Health)
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