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Growth and Reproductive Dysfunction in Metabolic Syndrome: Role of Dietary Intake and Supplement

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: closed (30 November 2020) | Viewed by 3832

Special Issue Editors


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Guest Editor

E-Mail Website
Guest Editor
Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
Interests: prevention, immunology, and immunotherapy of type 1 of mellitus diabetes; diagnosis and therapeutic management of mellitus diabetes; relationship between diabetes and cardiovascular diseases; the use of new technology concerning diabetes (insulin pumps, continuous glucose monitoring, an integrated insulin pump plus continuous glucose monitoring, telemedicine); gestational diabetes and diabetes during pregnancy; oxidative stress in diabetes; diabetic neuropathy and its involvement in cardiac and lung function; metabolic syndrome

Special Issue Information

Dear Colleagues,

It is well known that the dietary approach is a key milestone in the treatment of metabolic syndrome, especially in the prevention of cardiovascular consequences and evolution to type 2 diabetes. However, other effects of metabolic dysregulations are less investigated under the profile of the role of diet. Some examples of these include bone metabolism, reproductive questions both in male and females, cognitive impairment, and oncological risk; the entire lifespan, from early childhood to old age, is therefore involved. Growth hormone secretion is profoundly affected by diet; moreover, its metabolic functions are fundamental also in adult age, as suggested by the development of metabolic syndrome in adult growth hormone deficiency. Moreover, the aspect of nutraceutics and antioxidant supplements, which is more extensively studied, has still no scientific and univocal evidence. Therefore, the aim of this Special Issue is to provide new insights into the abovementioned topics. 

All original papers and reviews will be considered for this Special Issue, which could be of interest for endocrinologists, dieticians, general practitioners, gynecologists and andrologists, and pediatricians. 

Due to your extensive and eminent competence the field, it would be an honour to receive a contribution from you for the present project.

Prof. Dr. Antonio Mancini
Prof. Dr. Dario Pitocco
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Metabolic syndrome
  • Insulin therapy
  • Growth disorders
  • Male and female infertility
  • Adult growth
  • hormone deficiency
  • Bone metabolism

Published Papers (1 paper)

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Review

24 pages, 1296 KiB  
Review
The “Adipo-Cerebral” Dialogue in Childhood Obesity: Focus on Growth and Puberty. Physiopathological and Nutritional Aspects
by Carmine Bruno, Edoardo Vergani, Michele Giusti, Alessandro Oliva, Clelia Cipolla, Dario Pitocco and Antonio Mancini
Nutrients 2021, 13(10), 3434; https://doi.org/10.3390/nu13103434 - 28 Sep 2021
Cited by 9 | Viewed by 3415
Abstract
Overweight and obesity in children and adolescents are overwhelming problems in western countries. Adipocytes, far from being only fat deposits, are capable of endocrine functions, and the endocrine activity of adipose tissue, resumable in adipokines production, seems to be a key modulator of [...] Read more.
Overweight and obesity in children and adolescents are overwhelming problems in western countries. Adipocytes, far from being only fat deposits, are capable of endocrine functions, and the endocrine activity of adipose tissue, resumable in adipokines production, seems to be a key modulator of central nervous system function, suggesting the existence of an “adipo-cerebral axis.” This connection exerts a key role in children growth and puberty development, and it is exemplified by the leptin–kisspeptin interaction. The aim of this review was to describe recent advances in the knowledge of adipose tissue endocrine functions and their relations with nutrition and growth. The peculiarities of major adipokines are briefly summarized in the first paragraph; leptin and its interaction with kisspeptin are focused on in the second paragraph; the third paragraph deals with the regulation of the GH-IGF axis, with a special focus on the model represented by growth hormone deficiency (GHD); finally, old and new nutritional aspects are described in the last paragraph. Full article
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