The Interplay Between Nutrients and the Intestinal Barrier in Metabolic Liver Diseases: From Bench to Bedside
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".
Deadline for manuscript submissions: 25 July 2025 | Viewed by 87
Special Issue Editors
Interests: gut microbiota; intestinal permeability; metabolic dysfunction-associated steatotic liver disease (MASLD); chronic liver disorders; nutrition; nutrigenetics; nutrigenomics; immunity
Special Issues, Collections and Topics in MDPI journals
Interests: trained immunity; gut microbiota; intestinal permeability; metabolic dysfunction-associated steatotic liver disease (MASLD); chronic liver disorders; nutrition; nutrigenetics; liver cirrhosis; inflammation; oxidative stress
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Emerging evidence suggests the crucial role of nutrients and intestinal barrier alteration in the pathogenesis of dysmetabolic chronic liver disorders (CLDs), particularly metabolic dysfunction-associated steatotic liver disease (MASLD).
In the era of precision medicine, nutrigenetic/genomic approaches have progressively shown the active role of nutrients, revealing the mutual relationship between dietary elements and metabolic processes. Relevant findings have identified “pro-inflammatory” foods, elucidating their capability to disrupt immune pathways, ultimately promoting phlogosis and oxidative stress at local, hepatic, and systemic levels. Complementarily, the alteration of the bowel integrity barrier (“leaky gut”), which contributes to the crossing of substances, dramatically impacts this picture. Gut microbiota appears as a key regulator, influencing both nutrient transformation processes and intestinal permeability.
This Special Issue aims to provide new evidence about the complex relationship between gut microbiota, nutrition, and intestinal permeability in MASLD and dysmetabolic CLDs
Special attention will be given to studies elucidating the traits linking nutrients with the intestinal barrier’s homeostasis in this setting.
Manuscript submissions may include original research articles (clinical, translational, or basic research) and systematic reviews.
“From Bench to Bedside”, these studies can provide the basis for designing promising and effective management strategies for MASLD and dysmetabolic CLDs.
Prof. Dr. Alessandro Federico
Dr. Marcello Dallio
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- gut microbiota
- intestinal permeability
- metabolic dysfunction-associated steatotic liver disease (MASLD)
- chronic liver disorders
- nutrition
- nutrigenetics
- nutrigenomics
- trained immunity
- liver cirrhosis
- inflammation
- oxidative stress
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
