Advances in Sweeteners and Human Health: Metabolic, Molecular, and Epidemiological Perspectives on Safety, Efficacy, and Public Health Impact
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Carbohydrates".
Deadline for manuscript submissions: 15 April 2026 | Viewed by 2
Special Issue Editors
2, Department of Public Health, School of Medicine, University of Split, 21000 Split, Croatia
Interests: nutritional epidemiology; public health; healthcare management; analytical methods; genetic epidemiology
2. Department of Applied Pharmacy, School of Medicine, University of Split, 21000 Split, Croatia
Interests: toxicology; pharmacogenetics; healthcare management; public health; analytical methods
Special Issue Information
Dear Colleagues,
Sweeteners, both natural and artificial, have become prevalent in modern diets due to their ability to satisfy the sweet taste with reduced caloric intake. Their consumption affects multiple facets of human health, including metabolic regulation, gut microbiota composition, cardiovascular outcomes, cancer risk, behavioural responses, and psychological well-being. Despite a wealth of published studies, the evidence remains complex and often contradictory, with opinions sometimes exceeding the robustness of available data.
This Special Issue aims to provide a comprehensive and objective overview that fairly presents current scientific knowledge on sweeteners and human health. We invite rigorous original research articles, systematic reviews, and meta-analyses that critically evaluate the effects of sweeteners, openly acknowledging study limitations and alternative viewpoints. Narrative reviews will be carefully considered to ensure a balanced presentation rather than selective literature support.
By consolidating evidence-based findings and encouraging transparent discourse, we hope to inform clinicians, nutritionists, policymakers, and researchers, facilitating well-informed dietary guidance and regulatory policies on sweetener use. This Special Issue seeks to move beyond polarised debates and offer readers a full, nuanced understanding of the health implications associated with sweetener consumption.
Dr. Ajka Pribisalić
Dr. Davorka Sutlovic
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- artificial sweeteners
- non-nutritive sweeteners
- gut microbiota
- metabolic health
- obesity
- diabetes
- cardiovascular disease cancer risk
- side effects
- glycemic control
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