Underlying Signalings in the Neuro-Immune Communications
A special issue of Neurology International (ISSN 2035-8377).
Deadline for manuscript submissions: 31 August 2026 | Viewed by 1220
Special Issue Editors
Interests: autoimmunity; autoimmune diseases; inflammation; neuroinflammation; biomarkers; cytokines
Special Issues, Collections and Topics in MDPI journals
2. Multiprofile Hospital for Active Treatment “Uni Hospital”, 100 Georgi Benkovski Str., 4500 Panagyurishte, Bulgaria
3. Department of Neurology, University Multiprofile Hospital for Active Treatment in Neurology and Psychiatry "St. Naum", Medical University of Sofia, 1 Dr. Lyuben Rusev Str., 1113 Sofia, Bulgaria
Interests: autoimmune diseases of the central nervous system; cerebrovascular disease; neurodegenerative diseases
Special Issue Information
Dear Colleagues,
Interactions between the nervous and immune systems are increasingly recognized as key determinants of neurological disease onset, progression, and heterogeneity. Immune-mediated signaling influences neuronal survival, synaptic function, vascular integrity, and repair mechanisms, while neural and neurovascular pathways actively shape systemic and local immune responses. In clinical neurology, disruption of these bidirectional processes is evident across a broad range of conditions, including cerebrovascular disease, immune-mediated demyelinating disorders such as multiple sclerosis, neurodegenerative diseases, and systemic conditions with neurological involvement.
This Special Issue aims to explore the signaling mechanisms underlying neuro-immune communication with a focus on their clinical relevance. We welcome contributions that clarify how molecular and cellular immune pathways translate into structural, functional, and phenotypic changes observed in patients, including processes such as inflammation-driven demyelination, remyelination failure, and progression independent of overt inflammatory activity. Studies addressing neurovascular and glial signaling, peripheral immune contributions, biomarkers of immune activity, and modulatory influences such as the gut–brain axis are particularly encouraged. Both experimental and clinical research, as well as translational studies linking mechanistic insights to diagnostic or therapeutic implications, are within scope.
By integrating mechanistic knowledge with clinical reasoning, this Special Issue seeks to support a more coherent understanding of neuro-immune signaling and its implications for disease stratification, prognosis, and targeted intervention in neurological practice.
Dr. Tsvetelina Velikova
Guest Editor
Dr. Georgi Vasilev
Guest Editor Assistant
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Neurology International is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neuro-immune communication
- neuroinflammation
- immune signaling
- demyelinating diseases
- multiple sclerosis
- cerebrovascular disease
- neurodegeneration
- neurovascular unit
- biomarkers
- clinical neurology
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
