New Insights into Movement Disorders

Special Issue Editor


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Guest Editor
Department of Neurology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
Interests: dynactin; axonal transport; amyotrophic lateral sclerosis; neurodegenerative disease

Special Issue Information

Dear Colleagues,

Movement disorders are a group of nervous system conditions that affect movement. There are many types of movement disorders that cause different symptoms. Symptoms of movement disorders include the following: ataxia, chorea, dystonia, functional movement disorder, multiple system atrophy, myoclonus, Parkinson's disease, Parkinsonism, progressive supranuclear palsy, restless legs syndrome, tardive dyskinesia, tourette syndrome, tremor, etc.

In order to improve the impact of movement disorders on people's lives, it is necessary for scholars to study the pathogenesis, treatment strategies, and intervention management of movement disorders.

This Special Issue will collect various studies on movement disorders, especially in terms of diagnostic techniques, pathogenesis, and treatment methods.

Dr. Kensuke Ikenaka
Guest Editor

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Keywords

  • movement disorders
  • neurorehabilitation
  • stroke
  • ataxia
  • gait
  • diagnosis
  • symptom monitoring
  • treatments
  • pathogenesis

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Published Papers (1 paper)

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Review

12 pages, 4114 KiB  
Review
Painful Legs and Moving Toes Syndrome: Case Report and Review
by Mihael Tsalta-Mladenov, Vladina Dimitrova and Silva Andonova
Neurol. Int. 2024, 16(6), 1343-1354; https://doi.org/10.3390/neurolint16060102 - 4 Nov 2024
Viewed by 689
Abstract
Introduction: Painful legs and moving toes (PLMT) syndrome is a rare movement disorder characterized by defuse lower limb neuropathic pain and spontaneous abnormal, involuntary toe movements. Objective: The objective was to present a rare case of PLMT syndrome with a triggering area in [...] Read more.
Introduction: Painful legs and moving toes (PLMT) syndrome is a rare movement disorder characterized by defuse lower limb neuropathic pain and spontaneous abnormal, involuntary toe movements. Objective: The objective was to present a rare case of PLMT syndrome with a triggering area in an adult patient due to multilevel discogenic pathology, to make a thorough review of this disorder and to provide a practical approach to its management. Case presentation: A 59-years-old male was admitted to the neurology ward with symptoms of defuse pain in the lower-back and the right leg accompanied by involuntary movements for the right toes intensified by tactile stimulation in the right upper thigh. Magnetic resonance imaging (MRI) revealed a multilevel discogenic pathology of the lumbar and cervical spine, with myelopathy at C5-C7 level. A medication with Pregabalin 300 mg/daily significantly improved both the abnormal toe movements and the leg pain. The clinical effect was constant during the 90-day follow-up without any adverse effects. Conclusion: Painful legs and moving toes (PLMT) is a condition that greatly affects the quality of life of patients, but which still remains less known by clinicians. Spontaneous resolution is rare, and oral medications are the first-line treatment. Pregabalin is a safe and effective treatment option for PLMT that should be considered early for the management of this condition. Other medication interventions, such as botulinum toxin injections, spinal blockade, or non-pharmacological treatment options like spinal cord stimulation, and surgical decompressions, are also recommended when the conservative treatment is ineffective in well-selected patients. Full article
(This article belongs to the Special Issue New Insights into Movement Disorders)
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