Special Issue "Microscopy for Nanomedicine Research"

A special issue of Nanomaterials (ISSN 2079-4991).

Deadline for manuscript submissions: 30 November 2020.

Special Issue Editor

Dr. Sílvia Pujals
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Guest Editor
Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Baldiri Reixac 15-21, 08028 Barcelona, Spain
Department of Electronics and Biomedical Engineering, Faculty of Physics, Universitat de Barcelona, Barcelona, Spain.
Interests: nanomedicine; drug delivery; super resolution microscopy; electron microscopy; peptide chemistry

Special Issue Information

Dear Colleagues,

Nanomedicine arose 20 years ago with the promise to selectively deliver drugs at target sites, increasing their effectivity while minimizing undesired side effects. However, despite the great promise behind nanomedicine for drug delivery, very few products have been approved for patient use.

Different advanced microscopy techniques can guide in the path to find effective nanomedicines. From the robust characterization of nanomaterials to nanomaterials’ interaction with biological fluids and how they finally reach the target cell and organelle, microscopy can give information in each of these steps.

The potential information on nanomaterials that could be obtained from microscopy is very diverse: structure, morphology, size, surface roughness, surface charge, total number of ligands/particle, functional ligands/particle, atomic composition, etc.

Not only right after the nanomaterial formulation, but also on nanomaterial’s performance, microscopy can give important information. Protein corona formation, the EPR effect, transcytosis, extravasation, cellular targeting or the intracellular pathway of nanomedicines are some of the phenomena that can be studied using microscopy. Further, the stability of nanoformulation on different steps can potentially be followed, too.

Moreover, functional microscopy transcends pure structural information unveiling physical, chemical, and optical properties. Functional parameters like enzymatic activity, polarity, charge, pH, etc. of nanomaterials’ performance can be obtained with different microscopy techniques.

Finally, correlative techniques, usually applied to study biological processes, are starting to be used for nanomedicine.

Thus, microscopy no longer gives just a “photography” of the nanomaterial in time and space, but multidimensional information valuable for a robust nanomaterial characterization and to design more efficient nanomedicines.

Additionally, all the microscopy techniques applied for nanomedicine can also be used for nanotheranostic purposes.

The Special Issue of Nanomaterials will cover the aforementioned advances in different advanced microscopy techniques to be applied in nanomedicine.

Dr. Sílvia Pujals
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Nanomedicine
  • Nanomaterials
  • Nanoparticles
  • Drug delivery
  • Nanotheranostics
  • Light microscopy
  • Confocal laser scanning microscopy
  • Super resolution microscopy
  • In vivo optical imaging
  • Electron microscopy
  • Atomic force microscopy
  • Correlative microscopy
  • Functional microscopy

Published Papers

This special issue is now open for submission.
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