Nanomaterials for Matrix-Free Laser Desorption/Ionization Mass Spectrometry

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Nanophotonics Materials and Devices".

Deadline for manuscript submissions: 30 December 2024 | Viewed by 48

Special Issue Editors

E-Mail Website
Guest Editor
Nicolaus Copernicus University in Toruń, Centre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Torun, Torun, Poland
Interests: mass spectrometry; LDI-MS; biocolloids
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Nicolaus Copernicus University in Toruń, Centre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Toruń, Wileńska 4 Str., 87-100 Toruń, Poland
Interests: MALDI; SALDI; nanoparticles; mass spectrometry; metabolites
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Laser desorption/ionization (LDI) is one of the most popular ionization techniques currently used in mass spectrometry (MS). This technique is most commonly used in a variant of matrix-assisted laser desorption/ionization (MALDI), which uses a low-molecular-weight organic acid mixed with the sample to support the ionization process. However, this approach has some shortcomings, such as a high chemical background in the spectral region below an m/z of 700, making it difficult to analyze compounds giving signals in this spectral region, and inhomogeneous co-crystallization of analyte and matrix leading to the formation of so-called “sweet spots”, i.e., an inhomogeneous distribution of the analyte in the crystallizing matrix. For these reasons, increasing research attention is focused on the possibilities offered by the use of matrix-free systems based on nanostructures in laser methods, which are referred to as surface-assisted laser desorption/ionization (SALDI). The use of nanostructures in LDI MS has made it possible to analyze low molecular compounds, often at very low concentrations, without the presence of a matrix-derived chemical background, contributing to more applications of the LDI MS method.

In this Special Issue, we will discuss the latest information on the use of nanoparticles and nanostructures in matrix-free laser desorption/ionization mass spectrometry techniques.

Dr. Paweł Piotr Pomastowski
Dr. Adrian Arendowski
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • laser desorption/ionization
  • mass spectrometry
  • nanomaterials

Published Papers

This special issue is now open for submission.
Back to TopTop