MS-Based Metabolomic and Lipidomic Profiling in Urinary Tract Cancers
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Integrative Metabolomics".
Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 1328
Special Issue Editors
Interests: MALDI; SALDI; nanoparticles; mass spectrometry; metabolites
Special Issues, Collections and Topics in MDPI journals
Interests: nuclear magnetic resonance; metabolomics; bladder cancer; cardiovascular diseases; metabolism and exercise
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The development of mass spectrometry and combined techniques in recent years has allowed researchers to detect a large number of biological molecules and broaden our knowledge on the changes that take place in the cells of living organisms. Metabolites and lipids are important cellular components, and the recognition of changes in their composition can provide important information related to cellular homeostasis and disease pathogenesis. Cancer is a disease that alters cellular metabolism, so the metabolomic and lipidomic profiling of tissues and biofluids (such as serum and urine) seems to be the right approach to discovering new biomarkers. Urinary tract cancers, which include prostate, bladder, and kidney cancers, are among the most common cases and account for over 12% of all cancers. For some of these cancers, such as renal cell carcinoma, there are still no biomarkers with adequate sensitivity and specificity. Therefore, the profiling of changes in metabolites and lipids in order to search for differences, e.g., diagnostic and prognostic biomarkers of urinary tract cancers, remains an important challenge. In this Special Issue, we will discuss the latest information on the use of mass spectrometry methods for the metabolomics and lipidomics profiling of tissues and body fluids of patients with urological cancers.
Dr. Adrian Arendowski
Dr. Daniel Oscar Cicero
Guest Editors
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Keywords
- biomarkers
- bladder cancer
- kidney cancer
- lipids
- mass spectrometry
- metabolites
- metabolomic profiling
- prostate cancer
- renal cell carcinoma
- urological cancers
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