Design, Functionalization and Applications of Metal–Organic Framework (MOF)-Based Nanomaterials

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Synthesis, Interfaces and Nanostructures".

Deadline for manuscript submissions: 25 August 2025 | Viewed by 1056

Special Issue Editors


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Guest Editor
Department of Chemical and Biomedical Engineering, University of Missouri, Columbia, MO 65211, USA
Interests: application of MOFs in biological and biocatalytic processes; biomaterials based on enzyme@MOF composites; structure–function relationship of biomaterials

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Guest Editor
Department of Chemistry and Biochemistry, North Dakota State University, Fargo, ND 58102, USA
Interests: metal–organic frameworks; biomineralization; enzyme immobilization; enzyme stability; biocatalysis

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Guest Editor
Department of Chemical and Biomedical Engineering, University of Missouri, Columbia, MO 65211, USA
Interests: polymer chemistry and organic synthesis; EPR sensitive compounds; biochemical applications

Special Issue Information

Dear Colleagues,

We kindly invite you to submit your contribution to the Special Issue entitled “Design, Functionalization and Applications of Metal–Organic Framework (MOF)-Based Nanomaterials”. Nanomaterials have become essential components in modern research, industries, and everyday life. Metal–organic frameworks (MOFs) are unique porous materials with uniform, highly tunable, and highly diverse crystal structures, which endorse the broad applications of MOFs. Of particular interest are MOFs that are on the order of nanometer scales, which often result in obtaining properties of both nanomaterials and MOF-based porous materials. This Special Issue aims to present the current state of the art in the design, functionalization, and applications of MOF-based nanomaterials. Topics include, but are not limited to, the following: (i) design of MOF materials on the order of tens to a few hundred nanometers; (ii) modification or functionalization of regular nanomaterials with MOFs; (iii) hybridization or inclusion of biologically active molecules, including enzymes in MOF- and/or nanoparticle-based biomaterials; and (iv) applications of all materials listed in photochemistry/physics, biomedicine, biomaterials, chemical/biochemical catalysis, coatings, membrane science, separation, environmental protection, and controlled delivery. Green synthesis and green chemistry-related topics based on MOF materials are also very welcome.

The main goal of this Special Issue is to summarize the most up-to-date findings on the relevant topics. Up-to-date original research and reviews on these topics are welcome, and we look forward to receiving your contributions.

Dr. Zhongyu Yang
Dr. Zoe Armstrong
Dr. Li Feng
Guest Editors

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Keywords

  • metal–organic frameworks
  • nanomaterials
  • functionalization and size control in MOFs
  • functionalization of nanoparticles
  • enzyme encapsulation in MOFs
  • enzyme immobilization on nanomaterials
  • MOFs in photochemistry/physics
  • MOFs in chemical/biochemical catalysis
  • MOFs in environmental protection
  • MOFs in controlled delivery

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Published Papers (1 paper)

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Review

37 pages, 5131 KiB  
Review
Coating Metal–Organic Frameworks (MOFs) and Associated Composites on Electrodes, Thin Film Polymeric Materials, and Glass Surfaces
by Md Zahidul Hasan, Tyeaba Tasnim Dipti, Liu Liu, Caixia Wan, Li Feng and Zhongyu Yang
Nanomaterials 2025, 15(15), 1187; https://doi.org/10.3390/nano15151187 - 2 Aug 2025
Viewed by 660
Abstract
Metal–Organic Frameworks (MOFs) have emerged as advanced porous crystalline materials due to their highly ordered structures, ultra-high surface areas, fine-tunable pore sizes, and massive chemical diversity. These features, arising from the coordination between an almost unlimited number of metal ions/clusters and organic linkers, [...] Read more.
Metal–Organic Frameworks (MOFs) have emerged as advanced porous crystalline materials due to their highly ordered structures, ultra-high surface areas, fine-tunable pore sizes, and massive chemical diversity. These features, arising from the coordination between an almost unlimited number of metal ions/clusters and organic linkers, have resulted in significant interest in MOFs for applications in gas storage, catalysis, sensing, energy, and biomedicine. Beyond their stand-alone properties and applications, recent research has increasingly explored the integration of MOFs with other substrates, particularly electrodes, polymeric thin films, and glass surfaces, to create synergistic effects that enhance material performance and broaden application potential. Coating MOFs onto these substrates can yield significant benefits, including, but not limited to, improved sensitivity and selectivity in electrochemical sensors, enhanced mechanical and separation properties in membranes, and multifunctional coatings for optical and environmental applications. This review provides a comprehensive and up-to-date summary of recent advances (primarily from the past 3–5 years) in MOF coating techniques, including layer-by-layer assembly, in situ growth, and electrochemical deposition. This is followed by a discussion of the representative applications arising from MOF-substrate coating and an outline of key challenges and future directions in this rapidly evolving field. This article aims to serve as a focused reference point for researchers interested in both fundamental strategies and applied developments in MOF surface coatings. Full article
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