Design and Synthesis of Organic Molecules as Antineoplastic Agents

Dear Colleagues,

The fight against cancer can be dealt with, among different approaches, by synthetizing new compounds with high effectiveness and selectivity to the targeting cancer cells by concomitantly reducing side effects.

In this context, synthetic organic chemistry plays a key role and constitutes a flexible tool since it gives access to a great number of compounds, including antitumoral molecules present in nature, but which are not readily available, as well as novel drugs exhibiting anticancer actions. Through the variation of functional groups or motifs within the organic architecture, it is possible to find and modulate structure–activity relationships and, once the molecular target has been identified, to design new molecules or structural hybrids. Original articles, as well as reviews, regarding recent advancements in the design and synthesis of organic molecules of interest as antineoplastic agents are greatly welcome for inclusion in this Special Issue of Molecules.

Prof. Dr. Carla Boga
Dr. Gabriele Micheletti
Guest Editors

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