Special Issue "Cyclic Peptide Analogues and Non-peptide Mimetics"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (31 December 2020).
Interests: organic; peptide and medicinal chemistry; rational design and synthesis of linear; cyclic peptide analogues and non-peptide mimetics; conformational studies; molecular modelling of bioactive and pharmaceutical compounds; interactions of bioactive molecules (docking studies); pharmacophore analysis; homology modelling
It is a great pleasure and honour for me to ask for your contribution to a Special Issue related to cyclic peptides and non-peptide mimetics. This significant and timely topic inaugurates new opportunities in the design, discovery, and development of pharmaceutical products. Peptides and proteins are significant tools for drug development and are considered attractive "drug leads" for the rational design of bioactive molecules and molecules for medical use. The growing interest in peptide-based drugs in medicinal research provides many opportunities for the development of cyclic peptides and non-peptide mimetics aiming for the treatment of several diseases. Peptide cyclization and peptidomimetics restrict the conformational flexibility of their linear counterparts, and result in increased metabolic stability and receptor selectivity, therefore providing a better pharmacological profile. The knowledge of the bioactive conformation of linear peptides in combination with structure activity relations studies (SARs) are the main tools for the "structure-based design" and development of potent cyclic peptides and non-peptide mimetics.
The principal goal of this Special Issue is to provide the scientific community with novel approaches and directions in the field of rational drug design and medicinal chemistry, using cyclic peptides and non-peptide mimetics. I cordially invite researchers working in this field to join this Issue and submit original research articles, short communications, and review articles.
Assoc. Prof. Dr. Theodore Tselios
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Cyclic peptides
- Peptidomimetics and non-peptide mimetics
- Rational design of bioactive molecules
- Bioactive cyclic peptides