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Forensic Analytical Chemistry 2.0

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".

Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 3806

Special Issue Editor


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Guest Editor
Institute of Forensic Medicine, Department of Biomedical Engineering, University of Basel, 4056 Basel, Switzerland
Interests: forensic chemistry; toxicology; analytical chemistry; doping

Special Issue Information

Dear Colleagues,

Forensic toxicologists and chemists are continuously confronted with new challenges. The rapid evolution of new psychoactive drugs (NPS) and associated complications in detecting NPS are only two of these. Others encompass the interpretation of analytical findings, e.g., via conclusive marker substances together with improved knowledge of pharmacodynamics and -kinetics.

There are various challenges and limitations still associated with, or arising from, the constantly advancing Forensics knowledge base. This Special Issue approaches these challenges by proposing and discussing new and innovative solutions. Scientists are particularly encouraged to present studies that clearly demonstrate scientifically sound thinking that is “outside the box” to overcome current limitations in analytics and result interpretation (e.g., using biosensor approaches for detection, artificial intelligence, new diagnostic biomarkers, evaluation of substance toxicity, analysis of alternative matrices, etc.).

The special forensics issue is not limited to sophisticated new analytical approaches that tackle current challenges. Work is welcomed on closing forensics knowledge gaps by introducing new approaches beyond the current state of the art. Approaches can comprise new methodologies, e.g., biosensor technologies, the evaluation of new diagnostic markers, metabolomics, pharmacogenomics, alternative matrices, chemometrics, as well as new spheres of activities, including doping.

Dr. Katja Mercer-Chalmers-Bender
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • methodologies
  • biosensor technologies
  • biomarkers
  • substance toxicity

Published Papers (1 paper)

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Review

16 pages, 5183 KiB  
Review
State-of-the-Art Analytical Approaches for Illicit Drug Profiling in Forensic Investigations
by Reem Ahmed, Mohamad J. Altamimi and Mayssa Hachem
Molecules 2022, 27(19), 6602; https://doi.org/10.3390/molecules27196602 - 5 Oct 2022
Cited by 8 | Viewed by 3569
Abstract
In forensic chemistry, when investigating seized illicit drugs, the profiling or chemical fingerprinting of drugs is considered fundamental. This involves the identification, quantitation and categorization of drug samples into groups, providing investigative leads such as a common or different origin of seized samples. [...] Read more.
In forensic chemistry, when investigating seized illicit drugs, the profiling or chemical fingerprinting of drugs is considered fundamental. This involves the identification, quantitation and categorization of drug samples into groups, providing investigative leads such as a common or different origin of seized samples. Further goals of drug profiling include the elucidation of synthetic pathways, identification of adulterants and impurities, as well as identification of a drug’s geographic origin, specifically for plant-derived exhibits. The aim of this state-of-art-review is to present the traditional and advanced analytical approaches commonly followed by forensic chemists worldwide for illicit drug profiling. We discussed numerous methodologies for the physical and chemical profiling of organic and inorganic impurities found in illicit drug. Applications of powerful spectroscopic and chromatographic tools for illicit drug profiling including isotope-Ratio mass spectrometry (IRMS), gas chromatography–mass spectrometry (GC-MS), gas chromatography–isotope ratio mass spectrometry (GC-IRMS), ultra-high-performance liquid chromatography (UHPLC), thin layer chromatography (TLC), liquid chromatography–mass spectrometry (LC-MS) and inductively coupled plasma-mass spectrometry (ICP-MS) were discussed. Altogether, the techniques covered in this paper to profile seized illicit drugs could aid forensic chemists in selecting and applying a suitable method to extract valuable profiling data. Full article
(This article belongs to the Special Issue Forensic Analytical Chemistry 2.0)
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