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Plant-Based Food Science: Chemical Composition and Biological Activity—2nd Edition

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 730

Special Issue Editors


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Guest Editor
The Institute of Adriatic Culture and Karst Restoration, University of Split, Split, Croatia
Interests: food quality; analytics of olive oil; sensory analysis; polyphenolic potential of fruit and vegetable
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Faculty of Science Department of Chemistry, University of Split, Split, Croatia
Interests: chromatography; spectroscopy; biochemical analysis of food; bioactive heterocyclic compounds
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue will present research investigating the chemical composition and biologically active compounds isolated from plants. It will also address the methods used to isolate individual groups of chemical compounds and their subsequent chemical analysis. The determination of the biological activity of certain chemical compounds, such as polyphenols, tocopherols, and anthocyanins, underlines their importance. Results related to the antioxidant, antitumor, and microbiological activities of individual compounds or groups of compounds from plant sources are able to elucidate the potential applications of these chemical substances.

Authors are invited to contribute original research and review articles that address the application of analytical data in food chemistry and biological activity assays. This comprehensive approach will provide important chemical information regarding the composition and potential applications of individual chemical compounds from plants. 

Dr. Maja Jukić Špika
Dr. Barbara Soldo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • plants
  • extraction
  • chemical composition
  • biologically active compounds
  • antioxidation
  • antitumor activity
  • microbiological activity

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Published Papers (1 paper)

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Research

15 pages, 625 KB  
Article
Phytochemical Profile, Extraction and Characterization of Bioactive Compounds from Industrial Hemp (Cannabis sativa L.) Felina 32 Variety
by Monika Haczkiewicz, Marta Świtalska, Jacek Łyczko, Joanna Wietrzyk and Anna Gliszczyńska
Molecules 2025, 30(20), 4148; https://doi.org/10.3390/molecules30204148 - 21 Oct 2025
Viewed by 504
Abstract
An efficient method for the simultaneous extraction of cannabinoids and terpenes from the leaves and flowers of Cannabis sativa L. (var. Felina 32) was developed. Extraction parameters, including solvent type, temperature, and pressure, were optimized, revealing that hexane enables high-yield cannabinoid recovery. Moreover, [...] Read more.
An efficient method for the simultaneous extraction of cannabinoids and terpenes from the leaves and flowers of Cannabis sativa L. (var. Felina 32) was developed. Extraction parameters, including solvent type, temperature, and pressure, were optimized, revealing that hexane enables high-yield cannabinoid recovery. Moreover, terpene composition was influenced by the extraction temperature. Two extracts with the highest cannabinoid content were selected for further study, Feli1 (64.76%) and Feli2 (61.32%), both obtained using hexane. Feli1, extracted at –55 °C, had a monoterpene-to-sesquiterpene ratio of 16.7% to 83.3%, while Feli2, extracted at 25 °C, showed a higher monoterpene content (25.2%) and lower sesquiterpene content (74.8%). Both extracts demonstrated selective antiproliferative activity against cancer cell lines, with reduced toxicity toward normal breast epithelial cells (MCF-10A). Feli2 showed slightly stronger antiproliferative effects, likely due to its higher monoterpene content. At low concentrations, both extracts stimulated the growth of MV4-11 leukemia and MDA-MB-468 triple-negative breast cancer (TNBC) cells, while higher concentrations led to growth inhibition. These stimulatory effects were weaker than those observed for pure Δ9-THC or CBD. Full article
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