Recent Advances in Organic Synthesis towards Novel Drug Designs

Dear Colleagues,

Presently, the major burden of healthcare concerns chronic non-communicable diseases, with unexpected pandemics adding to the complexity of the drug discovery process. It is estimated that 80% of healthcare resources contribute towards managing chronic diseases which are prevalent in community settings. Thus, pharmaceutical development in healthcare is a business which requires the support of cutting-edge research and development.

R&D-driven innovative solutions will require a substantial understanding of medicinal chemistry, organic synthesis, digital chemistry and other related expertise. The present Special Issue of Molecules will serve as a valuable resource summarizing the key advances and upcoming challenges in drug discovery. We invite leaders in the topic areas outlined below to contribute to this Special Issue.

Suggested structure:

1. Editorial: Shape of Pharmaceutical Landscape in 2050 – A Futuristic Perspective (Javed Iqbal and Sandeep Verma)

Fundamentals

2. Open Challenges in Discovery Pipeline

3. Structural Optimization in Drug Discovery

Selected Advances in Therapeutics

4. Inhibitors and Receptors as Drug Targets

5. Humanized Antibodies

Future Outlook

6. Precision and Personalized Medicine

7. Sustainable Approaches in Therapeutics

Prof. Dr. Sandeep Verma
Prof. Dr. Javed Iqbal
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• organic synthesis
• bioactive compounds
• drug designs
• medicinal chemistry
• drug discovery
• inhibitors
• drug targets