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Special Issue "Synthesis and Bioactivity of Coumarin and Coumarin Derivatives"

A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: 30 November 2019

Special Issue Editor

Guest Editor
Prof. Dr. Konstantinos E. Litinas

Aristotle University of Thessaloniki, Department of Chemistry, Thessaloniki, Greece
Website | E-Mail
Phone: +30 2310997864
Interests: organic synthesis; natural products synthesis; coumarin derivatives; purine derivatives; modified N-homonucleosides; synthesis of compounds with possible biological activity; application of organometallic reagents in organic synthesis (olefin metathesis, cross-coupling reactions); synthesis under microwaves

Special Issue Information

Dear Colleagues,

Coumarin (2H-1-benzopyran-2-one) is wide spread as an essential core moiety in a variety of natural products occurring in plants, bacteria, and fungi. Coumarin is synthesized in nature through the shikimate biosynthetic pathway, and it is also metabolized to hydroxycoumarins. Coumarins present interesting biological properties, such as anticoagulant, antibiotic, anti-inflammatory, antioxidant, anti-HIV, anticancer, thermal photosensitizing, vasodilator, and estrogenic activity.

Especially, hydroxycoumarin derivatives are used as anticoagulant, antibiotic, or choleretic drugs. 7-Aminocoumarins are useful as biological sensors showing fluorescence activity. Fused furanocoumarin derivatives are used for treating psoriasis, and they also exhibit anti-inflammatory, antibacterial, antifungal, and cytochrome P-450 inhibitor properties. Fused pyranocoumarins present anti-HIV, anticancer, anti-inflammatory, antifungal activities, and they play an important role in the regulation of root growth in different plants. Fused pyrrolocoumarins possess cytotoxic, anti-HIV, anti-inflammatory, photobiological, and antiproliferative properties. Fused pyridocoumarins present anticholinergic, antidiabetic, antiallergic, antipsychotic, and antimicrobial activities.

Prof. Dr. Konstantinos E. Litinas
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Coumarin synthesis
  • Coumarin bioactivity
  • Coumarin derivatives
  • Hydroxycoumarins
  • Aminocoumarins
  • Fused coumarins
  • Furanocoumarins
  • Pyranocoumarins
  • Pyrrolocoumarins
  • Pyridocoumarins

Published Papers

This special issue is now open for submission.
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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