Recent Advances in the Treatment of Diabetes Mellitus and Its Secondary Complications
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (6 June 2024)
Special Issue Editor
Special Issue Information
Dear Colleagues,
Diabetes mellitus is the most common metabolic endocrine disorder, as we all know. Diabetes mellitus is the third leading cause of death if all secondary complications are considered, according to the WHO and American Diabetes Mellitus. However, excluding secondary complications, it ranks seventh in terms of mortality and morbidity. In the case of diabetes mellitus, the secondary complications caused by this condition must be considered. Diabetes affects almost all organs, potentially worsening the condition. Neuropathy, nephropathy, retinopathy, and diabetes foot microvascular and macrovascular complications are the most common secondary complications. Diabetes causes long-term complications that develop gradually. Controlled glucose levels will become more difficult to achieve as time goes on, implying that there will be more long-term complications. The current Special Issue on the secondary complications of diabetes and their treatment aims to publish high-quality research articles and reviews that address diabetes management, abnormalities of secondary complications, and other diseases associated with diabetes. Potential Topics include but are not restricted to:
- New strategies/ approaches to managing secondary complications such as Stearoyl CoA dismutase, Acetyl CoA Carboxylase, Adiponectin/ Adipocyte complement-related protein 30, Hormone Sensitive Lipase (HSL) Inhibitors
- Recent development in the therapeutic approaches for glucose management such as Protein tyrosine phosphatase-1B (PTP1B) inhibitors, Glycogen synthase kinase-3 (GSK3) inhibitors, β3- Adrenergic receptor agonist, Retinoid X receptor, PPARα agonist, AMP-activated protein kinase
- Development of new target as a target for antihyperglycemic drug designing
Dr. Pranav Kumar Prabhakar
Guest Editor
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Keywords
- diabetes mellitus
- Secondary complications
- neuropathy
- retinopathy
- diabetic foot
- microvascular
- macrovascular
- glycemic control
- drug targets
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