Recent Opinion on Protein-Carbohydrate Interactions
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Chemical Biology".
Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 2446
Special Issue Editors
Interests: oligosaccharides; glycoconjugates; self-assembling peptides/glycopeptides; carbohydrate-protein interactions
Interests: chemical and enzymatic synthesis of therapeutically promising oligosaccharides and mimetics thereof and the investigation of carbohydrate/protein interactions by NMR, surface plasmon resonance, microcalorimetry, and molecular modeling
Special Issue Information
Dear Colleagues,
In this issue, we would like to focus on the mechanisms and features of the interaction (thermodynamic and kinetic aspect) of carbohydrates and glycomimetics with proteins, and not simply on a descriptive presentation of the carbohydrate-binding specificity of a protein. We await articles discussing carbohydrate epitopes and protein paratopes, methods for localizing and investigating them, and approaches to applying this knowledge to the design of pharmacologically relevant epitopes or their mimetics. The spatial epitopes as well as architectures of recognition sites cognate to them (paratopes) are of particular interest. Here, we are not limited to canonical lectins and anti-glycan antibodies—articles on the glycan modules (motifs) of enzymes and other polyfunctional and modular proteins are also welcome. Oligosaccharides, polysaccharides, glycopeptides, and molecular clusters/patterns are the protagonists of our release.
Prof. Dr. Nicolai V. Bovin
Prof. Dr. Beat Ernst
Guest Editors
Manuscript Submission Information
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Keywords
- oligosaccharides
- polysaccharides
- glycoconjugates
- peptides/glycopeptides
- carbohydrate-protein interactions
- epitopes
- molecular clusters/patterns
