New Trends in Functionalized Cyclodextrins

Dear Colleagues,

Cyclodextrins are known in particular for their ability to form inclusion complexes with various molecules, and this feature forms the basis of their application in the chromatography, catalysis, pharmacy, cosmetics, agro-food, and textile industries.

The chemical modification of cyclodextrins has increased interest in these molecules and provides an attractive approach for building multifunctional systems. Many functionalized cyclodextrins have been synthesized with the aim of tuning the features of the cavity and to add new unique properties to the saccharide unit. A variety of moieties, such as drugs, peptides, metal chelators, macrocycles, and others, have been linked to cyclodextrins with applications in supramolecular, pharmaceutical, and material chemistry, biomimicry, and separation sciences.

More recently, interest in these molecules has extended to the synthesis of cyclodextrin-based nanosystems. Thus, a variety of organic and hybrid nanoparticles have been studied, and among them, some prodrug nanoparticles have been approved for phase III clinical trials as nanotherapeutics for treating cancer.

This Special Issue welcomes submissions of research communications, papers, and reviews with the aim of describing the multiple aspects and applications of functionalized cyclodextrins and cyclodextrin-based nanosystems.

Prof. Dr. Graziella Vecchio
Guest Editor

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