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Synthesis, Characterization and Anticancer Activities of Metal Complexes

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Inorganic Chemistry".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 28

Special Issue Editor


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Guest Editor
Department of Human Biology, Anatomy Building, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa
Interests: bioinorganic chemistry; metal-based anticancer drugs; catalysis; main group organometallic chemistry
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Special Issue Information

Dear Colleagues,

I am excited to serve as the editor for this Special Issue devoted to the Synthesis, Characterisation and Anticancer Activities of Metal Complexes. In recent years, this field has witnessed remarkable progress. Many rationally designed metal complexes have demonstrated excellent anticancer profiles across a variety of cancer cell lines. In-depth biological studies have shed light on diverse cell death mechanisms and emphasized the essential role of the metal center in these processes.

One particularly promising area of advancement is the development of multimetallic complexes, which incorporate two or more metal atoms in well-defined structures, often bridged by coordinating ligands. These complexes offer the potential for synergistic effects and enhanced selectivity, with designs tailored to specifically target cancer cells while sparing healthy ones.
A future direction with significant promise is the translation of in vitro findings into in vivo studies using animal models—an important step toward preclinical development.

We warmly invite submissions of original research articles and reviews that fall within the scope of this exciting and evolving field. We look forward to your contributions and to highlighting the latest developments in this area.

Dr. Burgert Blom
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • in vitro activity
  • in vivo activity
  • metal complex
  • biological studies
  • anticancer activity
  • bimetallic complexes
  • mechanistic studies

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Published Papers

This special issue is now open for submission.
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