Tailored Fluorescent Probes for Selective Recognition of Heavy Metal Species
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".
Deadline for manuscript submissions: 31 December 2025
Special Issue Editor
Interests: fluorescent sensors; bioimaging; disease diagnosis; disease markers; biomolecular research
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue, titled “Tailored Fluorescent Probes for Selective Recognition of Heavy Metal Species”, aims to advance the development of highly selective and sensitive fluorescent sensors for detecting toxic heavy metal ions in environmental, biological, and food systems. Heavy metals, such as mercury, lead, and cadmium, present severe ecological and health risks due to their persistence and bioaccumulation. Addressing these challenges requires innovative probe designs that combine molecular engineering, advanced materials, and interdisciplinary approaches to achieve precise recognition, real-time monitoring, and multi-functional applications. Contributing authors are encouraged to explore novel strategies for enhancing probe performance, including the integration of fluorophores like BODIPY or pyrazoline derivatives into polymer matrices or nanomaterials, as well as mechanisms such as Förster resonance energy transfer (FRET) and coordination chemistry to improve detection limits and anti-interference capabilities.
The scope of this issue spans fundamental research and practical implementations, emphasizing probes capable of simultaneous multi-target detection (e.g., Cu2+/Fe3+ or Hg2+/Ag+ pairs) and applications in live-cell imaging, environmental remediation, and food safety analysis. Additionally, studies leveraging computational tools like density functional theory (DFT) to elucidate binding mechanisms or optimize probe design are welcome. This issue will also highlight the need for scalable synthesis, biocompatibility, and field-deployable solutions, fostering collaborations across nanotechnology, supramolecular chemistry, and data-driven sensor development. By bridging theoretical insights with experimental validation, this collection seeks to drive breakthroughs in smart sensing technologies for sustainable environmental and public health protection.
Dr. Ying Hu
Guest Editor
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Keywords
- fluorescent probes
- heavy metal detection
- selective recognition
- multi-target sensing
- environmental monitoring
- bioimaging
- food safety
- sensor design
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