Exploration of Intrinsic Resistance in Bacteria
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Antimicrobial Agents and Resistance".
Deadline for manuscript submissions: closed (30 June 2022) | Viewed by 7629
Special Issue Editor
Interests: Mycobacterium tuberculous; non-tuberculous mycobacteria (NTM); virulence; host–pathogen interaction; innate immunity; persistence; response to antibiotics; intrinsic resistance; drug discovery; bacteriophages
Special Issue Information
Dear Colleagues,
Bacterial pathogens have evolved innate strategies that enable genetically susceptible pathogen to resist killing by lethal doses of clinically available antibiotics. Intrinsic resistance is a major contributing factor for the development of persistent, chronic, and drug-resistant infections in clinics. Therefore, it is critical to identify and characterize origins of intrinsic resistance and to understand molecular mechanisms including the metabolic transition of the pathogen and the host environmental factors stimulating the antibiotic tolerance state in bacteria. Such knowledge is essential for advancements in new treatment interventions through targeting the virulence factors of intrinsic resistance and, subsequently, inhibiting mechanisms that lead to the development of drug resistance.
This research topic encourages original research articles, brief research reports, perspective, opinion articles and reviews laying foundation into the deep understanding of bacterial inherent mechanisms promoting the antimicrobial resistance and demonstrating innovative treatment strategies that can potentially increase the therapeutic efficacy of existing antibiotics.
Dr. Lia Danelishvili
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- infectious diseases
- bacterial pathogens
- microbial tolerance
- antibiotic resistance
- persistent infections
- efflux and influx systems
- cell wall permeability
- bacterial metabolism
- growth and metabolic rate
- omics data
- bacterial proteome
- new therapeutic strategies
- metabolism-based strategies
- metabolites to overcome antibiotic tolerance
- biofilm
- host environmental stresses
- hypoxia
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.