Research on Arboviruses
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Virology".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 38
Special Issue Editor
Special Issue Information
Dear Colleagues,
The Zika virus (ZIKV) gained global attention during the 2015–2016 epidemic due to its association with severe neurological issues such as microcephaly and Guillain–Barré syndrome. ZIKV, an RNA virus with a positive-sense genome, is transmitted via mosquitoes, sexual contact, maternal–fetal transmission, and blood transfusion. A study analyzed 1889 genomic deposits from NCBI, focusing on ZIKV’s global spread and transmission dynamics. Most samples came from the Americas (59%) and Asia (27%), with the Asian lineage predominating. In Africa (8%), the West African lineage was more prevalent. Human isolates comprised much of the dataset (77%), followed by deposits from mosquitoes (15%) and animals (2%). Field-collected mosquito samples—including eggs, larvae, and adult mosquitoes—tested positive for the East African ZIKV lineage, suggesting mosquito eggs could serve as viral reservoirs. The detection of ZIKV in mosquito eggs underscores their potential role in ZIKV persistence and highlights the importance of mosquitoes as active vectors in tropical and subtropical regions. This study emphasizes the value of genomic data to uncover the origins, transmission patterns, and evolutionary dynamics of ZIKV, providing key insights into the lineage diversity and epidemiological significance of this arbovirus.
Dr. Monica Ferreira Moreira
Guest Editor
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Keywords
- Zika virus (ZIKV)
- mosquito eggs
- Aedes aegypti
- ZIKV evolutionary dynamics
- East African ZIKV lineage
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