The Emergence and Escape of SARS-CoV-2 Variants: Molecular Perspectives
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Virology".
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 2756
Special Issue Editor
Special Issue Information
Dear Colleagues,
In late 2020, SARS-CoV-2 began to evolve, as characterized by the rapid emergence of many viral variants that has been associated with the increased transmissibility and immune escape. Neutralizing antibodies (nAbs) are proven to be the most effective COVID-19 combating solutions due to their higher specificity and lower biosafety risks; however, the transient emergence of new variants caused a swift failure of vaccines and put the fate of COVID-19 therapeutic drugs, particularly nAbs, in danger. In addition, diagnostic procedures faced issues that caused economical and health concerns.
In the fight to bring an end to the pandemic, this Special Issue aims to comprehend the current and future mutational landscape of SARS-CoV-2 and its impact on the increased transmission of the emerging variants and potential immune escape. Additionally, this issue invites studies that delineate strategies that could help toward the diagnosis of mutated variants and therapeutics of COVID-19. Studies that computationally/empirically address molecular aspects of de-escalated and emerging SARS-CoV-2 variants with respect to the immune response are highly encouraged for submission.
Dr. Masaud Shah
Guest Editor
Manuscript Submission Information
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Keywords
- SARS-CoV-2
- variants of concern
- immune escape
- COVID-19
- monoclonal antibodies therapy
- protein-protein interaction
- therapeutics
- vaccine
- antiviral drugs
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