New Advances in Sporothrix and Sporotrichosis
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Molecular Microbiology and Immunology".
Deadline for manuscript submissions: 30 November 2025
Special Issue Editors
Interests: Sporothrix schenckii; therapeutics; sporotrichosis
Interests: fungus-host interaction; environmental biotechnology; microbial ecology; waste valorization; sustainability
Special Issue Information
Dear Colleagues,
Sporotrichosis, historically considered a neglected mycosis, has recently gained prominence due to its expanding geographic distribution, zoonotic nature—especially involving domestic cats—and emergence as an opportunistic infection in immunocompromised patients. The Sporothrix genus displays strong ecological resilience, persisting in diverse environments, even those contaminated with heavy metals and other pollutants, which adds complexity to the eco-epidemiological landscape of the disease. Recent advances in genomics, transcriptomics, and proteomics have deepened our understanding of the molecular mechanisms underlying fungal adaptation, virulence, and host–pathogen interactions. Additionally, new genetic engineering tools have opened new avenues to evaluate cutting-edge pathways involved in disease mechanisms. In this context, epidemiological studies, innovations in diagnostics, antifungal therapy, and preventive strategies are urgently needed. This Special Issue invites multidisciplinary research that broadens our understanding of Sporothrix species, focusing on their biology, ecology, molecular and pathogenic mechanisms, and clinical management. It encourages submissions on novel diagnostics, innovative treatments, and therapeutic and prevention strategies for both human and veterinary sporotrichosis. Accepted contributions may include original research, reviews, short communications, and case reports. Key topics include, but are not limited to, environmental biology, zoonotic transmission, immune responses, diagnostic advancements, molecular tools, omics approaches, antifungal discovery, and immunotherapies. The aim is to foster a comprehensive understanding of this increasingly relevant fungal disease.
Dr. Sandro Pereira
Dr. Damiana Téllez-Martínez
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Sporothrix
- sporotrichosis
- fungus–environment interactions
- zoonotic transmission
- molecular diagnosis
- antifungal therapy
- omics approaches
- host–pathogen interactions
- immunotherapeutic strategies
- immune response
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