Virotherapy Based on Oncolytic Adenovirus
A Special Issue of Microorganisms (ISSN 2076-2607) belonging to the section "Virology".
Deadline for manuscript submissions: closed (31 July 2026) | Viewed by 233
Editors
Interests: microbial based immunotherapies; cancer immunology and imaging
Special Issues, Collections and Topics in MDPI journals
Interests: microbiology; host-pathogen interactions; microbial-based cancer therapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Oncolytic virus-based therapy consists of genetically modified viruses that selectively infect, replicate within, and kill cancer cells while leaving normal cells unharmed and triggering an anti-tumor immune response. To date, multiple oncolytic viruses are being tested preclinically and clinically. One of them is T-VEC, a herpes simplex virus approved for injection directly into tumors in melanoma patients. Among all oncolytic viruses, oncolytic adenovirus (OAd) is the most widely tested vector due to its many advantages. This makes OAd an excellent virotherapy agent for targeting not only direct tumor lysis but also immunotherapy. Therefore, in this Special Issue, we invite you to submit research articles, review articles, and short communications that showcase current research in the area of “Virotherapy Based on Oncolytic Adenovirus,” including, but not limited to, virus engineering, combination therapy, immunotherapy, overcoming OAd limitations, etc.
Dr. Jorge G. Gomez-Gutierrez
Dr. Paul De Figueiredo
Guest Editors
Manuscript Submission Information
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Keywords
- cancer
- oncolytic
- adenovirus
- virotherapy
- immunotherapy
- combined therapy
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