Pathogen Infection and Public Health

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 673

Special Issue Editors


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Guest Editor
1. Unidad de Investigación en Enfermedades Infecciosas, Laboratorio de Virología Clínica y Experimental, Hospital Infantil de México Federico Gómez, Mexico City, Mexico
2. Centro Interdisciplinario de Ciencias de la Salud, Departamento de Medicina, Unidad Milpa Alta, Instituto Politécnico Nacional, Mexico City, Mexico
Interests: population health; epidemiology; host-parasite interaction
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Departamento de Infectología, Hospital Infantil de México Federico Gómez, Instituto Nacional de Salud, Mexico City, Mexico
Interests: population health; epidemiology; host-parasite interaction

Special Issue Information

Dear Colleagues,

Since the emergence of humanity, pathogens have been responsible for outbreaks, epidemics, and pandemics that have profoundly affected human populations. Over time, valuable lessons have been learned from the observations of microbiologists, virologists, immunologists, mycologists, and epidemiologists. These insights have facilitated the development of effective preventive and corrective measures.

In today's world, new technologies enable a swift response to epidemics. In this regard, molecular biology and genetic innovations serve as essential tools that enhance public health initiatives in prevention, early detection, diagnosis, and treatment.

This Special Issue seeks to enhance our understanding of infectious diseases and their broader implications for public health. It focuses on exploring the impact of transmissible infectious diseases—including viral, bacterial, fungal, and parasitic infections—on diverse global population health, economic systems, migration patterns, or chronic diseases.

We invite the submission of original research articles, case reports, reviews, perspectives, opinions, and letters to the editor that contribute to the advancement of knowledge regarding pathogens in public health and their role in improving human health outcomes.

The scope of this Special Issue encompasses, but is not limited to, the following areas:

  1. Epidemiological patterns and the behavior of pathogens associated with outbreaks and epidemics.
  2. Public health strategies for the promotion of health and the prevention of pathogen transmission in healthcare settings and the broader community.
  3. Methodologies for effective pathogen control in public health environments.
  4. Prophylactic interventions designed to manage and mitigate the impact of pathogens in public health contexts.

Dr. José Arellano-Galindo
Dr. Ana Estela Gamiño-Arroyo
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • infectious diseases
  • transmissible infections
  • outbreaks
  • population health
  • the relationship between the economy and health
  • migration's impact on health

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Published Papers (1 paper)

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Research

10 pages, 2204 KiB  
Article
First Report of Genetic Resistance to Azithromycin in Treponema pallidum from Blood Samples Among Men Who Have Sex with Men and People Living with HIV from Mexico
by Dayana Nicté Vergara-Ortega, Perla J. Santibañez-Amador, Santa García-Cisneros, María Olamendi-Portugal, Everardo Gutiérrez-Millán, Antonia Herrera-Ortíz, Verónica Ruíz-González and Miguel Ángel Sánchez-Alemán
Microorganisms 2025, 13(5), 1069; https://doi.org/10.3390/microorganisms13051069 - 3 May 2025
Viewed by 546
Abstract
Syphilis is a re-emerging sexually transmitted disease caused by Treponema pallidum subsp. pallidum (TPA). It especially affects vulnerable populations such as men who have sex with men (MSM) and people living with HIV. Despite being treatable with benzathine penicillin G, a substantial increase [...] Read more.
Syphilis is a re-emerging sexually transmitted disease caused by Treponema pallidum subsp. pallidum (TPA). It especially affects vulnerable populations such as men who have sex with men (MSM) and people living with HIV. Despite being treatable with benzathine penicillin G, a substantial increase in TPA resistance to azithromycin has been reported in many countries. The objective of this study was to detect the resistance of T. pallidum (TPA) to macrolides in blood samples from men who have sex with men and people living with HIV using molecular methods in a cross-sectional study. The detection of both TPA and the resistance to azithromycin was achieved through molecular methodologies (nested PCR), which were applied to blood samples of people with asymptomatic syphilis. We report the first data on the molecular prevalence of TPA and the first identification of genetic resistance to azithromycin (punctual mutation A2058G) in Mexico. Resistance testing for syphilis is not routinely performed in Mexico, but azithromycin continues to be prescribed despite syphilis being treatable with benzathine penicillin G. Therefore, the surveillance of cases of syphilis treatment failure, especially in vulnerable populations, which are the population group that maintains the active transmission of TPA, is recommended. Full article
(This article belongs to the Special Issue Pathogen Infection and Public Health)
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